Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT3 | P36888 | 12/20 | 0.49 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.43 |
| ▸ | MBD2 | Q9UBB5 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13394331 | 0.84 | F2RL3 (0.55) | FLT3F2RL3MBD2CA12CA1 | |
| SCHEMBL15079640 | 0.79 | FLT3 (0.56) | FLT3 | |
| SCHEMBL16219331 | 0.76 | F2RL3 (0.46) | F2RL3MBD2CA12CA1CA2 | |
| SCHEMBL15079505 | 0.76 | F2RL3 (0.46) | F2RL3MBD2CA12CA1CA2 | |
| SCHEMBL17706307 | 0.75 | FLT3 (0.86) | FLT3 | |
| SCHEMBL13394346 | 0.73 | F2RL3 (0.40) | FLT3F2RL3MAPTTP53RAB9A | |
| SCHEMBL15079500 | 0.73 | FLT3 (0.48) | FLT3F2RL3MBD2CA12CA2 | |
| SCHEMBL13394606 | 0.71 | F2RL3 (0.37) | FLT3F2RL3MAPTTP53RAB9A | |
| SCHEMBL15079607 | 0.70 | F2RL3 (0.43) | FLT3F2RL3MBD2CA12CA1 | |
| SCHEMBL13539252 | 0.69 | LMNA (0.53) | F2RL3MBD2MAPTTP53RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013091502-A1 | TRI-HETEROCYCLIC DERIVATIVES, PREPARATION PROCESS AND USES THEREOF | SHANGHAI DE NOVO PHARMATECH CO LTD. (CN) | 2013-06-27 | — | — | WO | disclosed |