Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 3/20 | 0.46 |
| ▸ | CA1 | P00915 | 3/20 | 0.46 |
| ▸ | CA2 | P00918 | 3/20 | 0.46 |
| ▸ | CA9 | Q16790 | 3/20 | 0.46 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | FPR1 | P21462 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | EYA2 | O00167 | 1/20 | 0.33 |
| ▸ | APP | P05067 | 1/20 | 0.33 |
| ▸ | ACE | P12821 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15080653 | 0.84 | CA12 (0.48) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL1547062 | 0.83 | CA1 (0.56) | CA12CA1CA2CA9PIK3CD | |
| SCHEMBL6534981 | 0.82 | CA12 (0.46) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL17424485 | 0.80 | CA12 (0.35) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL29669460 | 0.80 | CA1 (0.54) | CA12CA1CA2CA9PIK3CD | |
| SCHEMBL16650139 | 0.80 | CA12 (0.45) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL2687920 | 0.80 | TDP1 (0.43) | HSD17B10TDP1EYA2APPACE | |
| SCHEMBL7938759 | 0.78 | CA1 (0.52) | CA12CA1CA2CA9PIK3CD | |
| SCHEMBL6788905 | 0.78 | TDP1 (0.41) | HSD17B10TDP1EYA2APPACE | |
| Water SCHEMBL7765705 | 0.78 | TDP1 (0.41) | HSD17B10TDP1EYA2APPACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170058002-A1 | GAMMA-AAPEPTIDES WITH POTENT AND BROAD-SPECTRUM ANTIMICROBIAL ACTIVITY | UNIVERSITY OF SOUTH FLORIDA (US) | 2017-03-02 | — | — | US | disclosed |
| US-9499587-B2 | Gamma-AApeptides with potent and broad-spectrum antimicrobial activity | UNIVERSITY OF SOUTH FLORIDA (US) | 2016-11-22 | — | — | US | disclosed |
| US-20150274782-A1 | GAMMA-AAPEPTIDES WITH POTENT AND BROAD-SPECTRUM ANTIMICROBIAL ACTIVITY | UNIVERSITY OF SOUTH FLORIDA (US) | 2015-10-01 | — | — | US | disclosed |
| US-8476224-B2 | Macrocycles and their uses | NOVARTIS AG (US) | 2013-07-02 | — | — | US | disclosed |
| CN-1278790-A | Chemical compound | ASTRA ZENECA BRITISH INC (GB) | 2001-01-03 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150274782-A1 | GAMMA-AAPEPTIDES WITH POTENT AND BROAD-SPECTRUM ANTIMICROBIAL ACTIVITY | ANPEP, DNPEP, ENPEP | CA12 4464/4885CA1 4738/4885CA2 4295/4885 |
| US-20170058002-A1 | GAMMA-AAPEPTIDES WITH POTENT AND BROAD-SPECTRUM ANTIMICROBIAL ACTIVITY | ANPEP, DNPEP, ENPEP | CA12 4464/4885CA1 4738/4885CA2 4295/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.