Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 11/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 10/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 10/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 2/20 | 0.35 |
| ▸ | DRD3 | P35462 | 3/20 | 0.33 |
| ▸ | DRD2 | P14416 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6946241 | 0.90 | SLC6A4 (0.57) | SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL3364988 | 0.85 | SLC6A4 (0.69) | SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL6945394 | 0.85 | SLC6A4 (0.69) | SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL3364991 | 0.85 | SLC6A4 (0.69) | SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL7969941 | 0.79 | SMN1; SMN2 (0.43) | TP53DRD2 | |
| SCHEMBL15080462 | 0.79 | SMN1; SMN2 (0.43) | TP53DRD2 | |
| SCHEMBL7954787 | 0.70 | SLC6A4 (0.48) | SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL6946224 | 0.68 | SLC6A2 (0.42) | SLC6A4SLC6A2SLC6A3TP53DRD3 | |
| SCHEMBL1002832 | 0.67 | PRSS1 (0.61) | ALDH1A1HPGDPARP1 | |
| SCHEMBL29503140 | 0.67 | PRSS1 (0.61) | ALDH1A1HPGDPARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8475804-B2 | Compositions and methods for treatment of filovirus-mediated diseases | U.S. ARMY MEDICAL RESEARCH AND MATERIAL COMMAND (US) | 2013-07-02 | — | — | US | disclosed |