Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 20/20 | 0.72 |
| ▸ | HRH3 | Q9Y5N1 | 9/20 | 0.64 |
| ▸ | HTR2A | P28223 | 2/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.52 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7970315 | 0.85 | SLC6A4 (0.56) | SLC6A4HRH3HTR2AKCNH2SLC6A3 | |
| Uk-390957 SCHEMBL931652 | 0.84 | SLC6A4 (1.00) | SLC6A4HTR2AKCNH2SLC6A3SLC6A2 | |
| SCHEMBL6152231 | 0.84 | SLC6A4 (0.57) | SLC6A4HRH3HTR2AKCNH2SLC6A3 | |
| SCHEMBL3361902 | 0.84 | SLC6A4 (0.76) | SLC6A4HRH3HTR2AKCNH2SLC6A3 | |
| SCHEMBL7741453 | 0.83 | SLC6A4 (0.59) | SLC6A4HRH3HTR2AKCNH2SLC6A3 | |
| SCHEMBL7735932 | 0.81 | SLC6A4 (0.63) | SLC6A4HTR2AKCNH2SLC6A3SLC6A2 | |
| SCHEMBL6151338 | 0.80 | SLC6A4 (1.00) | SLC6A4HRH3HTR2AKCNH2SLC6A3 | |
| SCHEMBL7741889 | 0.79 | SLC6A4 (0.57) | SLC6A4HTR2AKCNH2 | |
| SCHEMBL6151957 | 0.78 | SLC6A4 (0.71) | SLC6A4HRH3HTR2AKCNH2SLC6A3 | |
| SCHEMBL6951883 | 0.78 | SLC6A4 (0.71) | SLC6A4HRH3HTR2AKCNH2SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8475804-B2 | Compositions and methods for treatment of filovirus-mediated diseases | U.S. ARMY MEDICAL RESEARCH AND MATERIAL COMMAND (US) | 2013-07-02 | — | — | US | disclosed |