Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 18/20 | 0.63 |
| ▸ | HTR2A | P28223 | 11/20 | 0.63 |
| ▸ | KCNH2 | Q12809 | 9/20 | 0.63 |
| ▸ | SOS1 | Q07889 | 2/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7741889 | 0.89 | SLC6A4 (0.57) | SLC6A4HTR2AKCNH2SOS1 | |
| SCHEMBL3361902 | 0.87 | SLC6A4 (0.76) | SLC6A4HTR2AKCNH2SOS1SLC6A3 | |
| SCHEMBL8365604 | 0.87 | SLC6A4 (0.52) | SLC6A4HTR2AKCNH2SOS1SLC6A3 | |
| SCHEMBL7740496 | 0.86 | SLC6A4 (0.51) | SLC6A4HTR2AKCNH2SOS1SLC6A3 | |
| SCHEMBL7970315 | 0.84 | SLC6A4 (0.56) | SLC6A4HTR2AKCNH2SOS1SLC6A3 | |
| SCHEMBL15080486 | 0.81 | SLC6A4 (0.72) | SLC6A4HTR2AKCNH2SLC6A3SLC6A2 | |
| SCHEMBL6152231 | 0.80 | SLC6A4 (0.57) | SLC6A4HTR2AKCNH2SOS1SLC6A3 | |
| SCHEMBL7741453 | 0.79 | SLC6A4 (0.59) | SLC6A4HTR2AKCNH2SOS1SLC6A3 | |
| SCHEMBL7067210 | 0.78 | SLC6A4 (0.54) | SLC6A4HTR2AKCNH2SOS1SLC6A3 | |
| SCHEMBL7065184 | 0.78 | SLC6A4 (0.48) | SLC6A4HTR2AKCNH2SOS1SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100009970-A1 | COMPOSITIONS AND METHODS FOR TREATMENT OF VIRAL DISEASES | COMBINATORX (SINGAPORE) PTE. LTD. (SG) | 2010-01-14 | — | — | US | disclosed |
| US-20100009970-A1 | COMPOSITIONS AND METHODS FOR TREATMENT OF VIRAL DISEASES | COMBINATORX (SINGAPORE) PTE. LTD. (SG) | 2010-01-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100009970-A1 | COMPOSITIONS AND METHODS FOR TREATMENT OF VIRAL DISEASES | HTR1A, HTR3B, HTR3A | SLC6A4 34/4885HTR2A 10/4885KCNH2 1523/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.