Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | KDM6B | O15054 | 1/20 | 0.35 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.35 |
| ▸ | CCNC | P24863 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | CDK8 | P49336 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | CA9 | Q16790 | 2/20 | 0.33 |
| ▸ | LATS1 | O95835 | 1/20 | 0.33 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.33 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | CRHBP | P24387 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13947026 | 0.81 | IDO1 (0.41) | IDO1KDM6BKDM4CHTTNR4A2 | |
| SCHEMBL11991397 | 0.76 | IDO1 (0.40) | IDO1KDM6BKDM4CS1PR4 | |
| SCHEMBL18878176 | 0.74 | CCR1 (0.37) | S1PR4ALDH1A1MAPTRAB9A | |
| Hydrochloric Acid SCHEMBL28953693 | 0.72 | CCR1 (0.36) | S1PR4ALDH1A1MAPTRAB9A | |
| SCHEMBL18884313 | 0.72 | ADORA2A (0.39) | S1PR4ALDH1A1MAPTRAB9A | |
| SCHEMBL22593396 | 0.72 | CCR1 (0.36) | S1PR4ALDH1A1MAPTRAB9A | |
| SCHEMBL19760125 | 0.70 | GLO1 (0.58) | GAANR4A2ALDH1A1MAPTRAB9A | |
| SCHEMBL8308782 | 0.69 | APP (0.40) | CCNCHTTCDK8LATS1SLC2A1 | |
| SCHEMBL28571824 | 0.67 | IDO1 (0.36) | IDO1HTTGAAS1PR4NPC1 | |
| SCHEMBL13947192 | 0.67 | IDO1 (0.39) | IDO1KDM6BKDM4CGAANR4A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8912182-B2 | Viral polymerase inhibitors | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2014-12-16 | — | — | US | disclosed |
| US-8541402-B2 | Viral polymerase inhibitors | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2013-09-24 | — | — | US | disclosed |
| US-8476257-B2 | Viral polymerase inhibitors | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2013-07-02 | — | — | US | disclosed |