Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.53 |
| ▸ | MAPT | P10636 | 7/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | XDH | P47989 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.40 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.40 |
| ▸ | EP300 | Q09472 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | APP | P05067 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14734850 | 0.83 | MAPT (0.45) | ALDH1A1MAPTRXFP1XDHSMN1; SMN2 | |
| SCHEMBL8446009 | 0.83 | MAPT (0.45) | ALDH1A1MAPTXDHSMN1; SMN2LMNA | |
| SCHEMBL3563637 | 0.81 | APP (0.50) | ALDH1A1MAPTSMN1; SMN2LMNAGAA | |
| SCHEMBL3563633 | 0.81 | APP (0.50) | ALDH1A1MAPTSMN1; SMN2LMNAGAA | |
| SCHEMBL19240095 | 0.80 | APP (0.43) | ALDH1A1MAPTRXFP1XDHSMN1; SMN2 | |
| SCHEMBL10589671 | 0.78 | HSP90AA1 (0.48) | ALDH1A1MAPTRXFP1SMN1; SMN2LMNA | |
| SCHEMBL8121820 | 0.77 | NPC1 (0.45) | ALDH1A1MAPTSMN1; SMN2LMNATSHR | |
| SCHEMBL8362622 | 0.77 | KMT2A (0.46) | ALDH1A1MAPTLMNAGAATSHR | |
| SCHEMBL16465058 | 0.74 | ALDH1A1 (0.60) | ALDH1A1MAPTSMN1; SMN2LMNAGAA | |
| SCHEMBL3564987 | 0.74 | APP (0.46) | ALDH1A1MAPTSMN1; SMN2LMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8476433-B2 | Agent exhibiting the properties of a cognitive function promoter (embodiments) | UNIKORM (RU) | 2013-07-02 | — | — | US | disclosed |