Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.60 |
| ▸ | CRHBP | P24387 | 1/20 | 0.60 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.49 |
| ▸ | TSHR | P16473 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | USP2 | O75604 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20443706 | 0.95 | CRHBP (0.53) | SMN1; SMN2CRHBPCRHR2KMT2AMEN1 | |
| SCHEMBL22873669 | 0.85 | HRH4 (0.66) | KMT2AKDM4EALDH1A1HSD17B10TSHR | |
| SCHEMBL20443845 | 0.83 | KMT2A (0.64) | SMN1; SMN2CRHBPCRHR2KMT2AMEN1 | |
| SCHEMBL14528408 | 0.83 | MEN1 (0.53) | SMN1; SMN2CRHBPCRHR2KMT2AMEN1 | |
| SCHEMBL21796733 | 0.81 | MEN1 (0.51) | SMN1; SMN2CRHBPCRHR2KMT2AMEN1 | |
| SCHEMBL30067691 | 0.81 | HRH4 (0.53) | SMN1; SMN2CRHBPCRHR2KMT2AMEN1 | |
| SCHEMBL22873735 | 0.81 | HRH4 (0.43) | SMN1; SMN2CRHBPCRHR2KMT2AMEN1 | |
| SCHEMBL12409890 | 0.80 | SMN1; SMN2 (0.53) | SMN1; SMN2CRHBPCRHR2KMT2AMEN1 | |
| SCHEMBL12570455 | 0.79 | KMT2A (0.49) | SMN1; SMN2CRHBPCRHR2KMT2AMEN1 | |
| SCHEMBL5803078 | 0.79 | CRHBP (0.64) | SMN1; SMN2CRHBPCRHR2KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8476225-B2 | Antiviral compounds | GILEAD SCIENCES, INC. (US) | 2013-07-02 | — | — | US | disclosed |