Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNC | P24863 | 6/20 | 0.48 |
| ▸ | CDK8 | P49336 | 6/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | GRIN2B | Q13224 | 10/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | FLT3 | P36888 | 1/20 | 0.35 |
| ▸ | MYLK | Q15746 | 1/20 | 0.35 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.35 |
| ▸ | CILK1 | Q9UPZ9 | 1/20 | 0.35 |
| ▸ | CDK11A | Q9UQ88 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3517473 | 0.83 | CCNC (0.46) | CCNCCDK8NPSR1GRIN2BSMN1; SMN2 | |
| SCHEMBL2067150 | 0.78 | CCNC (0.43) | CCNCCDK8NPSR1SMN1; SMN2L3MBTL1 | |
| SCHEMBL10044956 | 0.71 | ALPI (0.50) | CCNCCDK8SMN1; SMN2FLT3MYLK | |
| SCHEMBL22305679 | 0.71 | GAA (0.50) | CCNCCDK8NPSR1GRIN2BSMN1; SMN2 | |
| SCHEMBL29050443 | 0.71 | CCNC (0.40) | CCNCCDK8NPSR1GRIN2BFLT3 | |
| SCHEMBL1703729 | 0.70 | CCNC (0.45) | CCNCCDK8FLT3MYLKAURKB | |
| SCHEMBL3514147 | 0.70 | NPSR1 (0.40) | CCNCCDK8NPSR1GRIN2BSMN1; SMN2 | |
| SCHEMBL2067815 | 0.70 | CCNC (0.39) | CCNCCDK8NPSR1GRIN2BFLT3 | |
| SCHEMBL26700263 | 0.70 | CCNC (0.37) | CCNCCDK8NPSR1GRIN2BSMN1; SMN2 | |
| SCHEMBL6865368 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021155321-A2 | COMPOUNDS AND USES THEREOF | FOGHORN THERAPEUTICS INC. (US) | 2021-08-05 | — | — | WO | disclosed |
| US-8476294-B2 | 1H-imidazo[4,5-c]quinolinone derivatives | NOVARTIS AG (CH) | 2013-07-02 | — | — | US | disclosed |