Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22326350 | 0.84 | GAA (0.88) | GAACYP1A2ALDH1A1CYP2C9RECQL | |
| SCHEMBL12028877 | 0.83 | GAA (0.64) | GAACYP1A2ALDH1A1CYP2C9RECQL | |
| SCHEMBL12155180 | 0.83 | GAA (0.64) | GAACYP1A2ALDH1A1CYP2C9RECQL | |
| SCHEMBL12143064 | 0.80 | GAA (0.58) | GAACYP1A2ALDH1A1CYP2C9RECQL | |
| SCHEMBL13515784 | 0.78 | GAA (0.57) | GAACYP1A2ALDH1A1CYP2C9RECQL | |
| SCHEMBL12028883 | 0.78 | GAA (1.00) | GAACYP1A2ALDH1A1CYP2C9RECQL | |
| SCHEMBL3077457 | 0.78 | GAA (1.00) | GAACYP1A2ALDH1A1CYP2C9RECQL | |
| SCHEMBL12029057 | 0.78 | GAA (1.00) | GAACYP1A2ALDH1A1CYP2C9RECQL | |
| SCHEMBL34474429 | 0.78 | SMN1; SMN2 (0.67) | GAAALDH1A1LMNAMAPTMEN1 | |
| SCHEMBL28463507 | 0.78 | SMN1; SMN2 (0.67) | GAAALDH1A1LMNAMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111196808-B | Diazabicyclo compounds and their use | 南京圣和药业股份有限公司 | 2022-10-18 | — | — | CN | disclosed |
| CN-113874074-A | HMOX1 inducers | 米托布里奇公司 | 2021-12-31 | — | — | CN | disclosed |
| CN-111196808-A | Diazabicyclo compounds and their use | 南京圣和药业股份有限公司 | 2020-05-26 | — | — | CN | disclosed |
| CN-106061480-B | Therapeutic inhibitory compounds | 莱福斯希医药公司 | 2020-02-28 | — | — | CN | disclosed |
| US-8791231-B2 | Compositions containing, methods involving, and uses of non-natural amino acids and polypeptides | AMBRX, INC. (US) | 2014-07-29 | — | — | US | disclosed |
| US-8476411-B2 | Compositions containing, methods involving, and uses of non-natural amino acids and polypeptides | AMBRX, INC. (US) | 2013-07-02 | — | — | US | disclosed |