Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.88 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.72 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.59 |
| ▸ | RECQL | P46063 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3077457 | 0.94 | GAA (1.00) | GAAALDH1A1CYP1A2RECQLKMT2A | |
| SCHEMBL12028883 | 0.94 | GAA (1.00) | GAAALDH1A1CYP1A2RECQLKMT2A | |
| SCHEMBL12029057 | 0.94 | GAA (1.00) | GAAALDH1A1CYP1A2RECQLKMT2A | |
| SCHEMBL6570943 | 0.91 | GAA (0.74) | GAAALDH1A1CYP1A2RECQLKMT2A | |
| SCHEMBL30804996 | 0.90 | GAA (0.72) | GAAALDH1A1CYP1A2RECQLKMT2A | |
| SCHEMBL1038374 | 0.90 | GAA (0.72) | GAAALDH1A1CYP1A2RECQLKMT2A | |
| SCHEMBL24507059 | 0.89 | GAA (0.71) | GAAALDH1A1CYP1A2RECQLKMT2A | |
| SCHEMBL13545621 | 0.88 | GAA (0.69) | GAAALDH1A1CYP1A2RECQLKMT2A | |
| SCHEMBL6625137 | 0.87 | GAA (0.69) | GAAALDH1A1CYP1A2RECQLKMT2A | |
| SCHEMBL2452322 | 0.87 | GAA (0.69) | GAAALDH1A1CYP1A2RECQLKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11180501-B2 | Crystal form of β-lactamase inhibitor and preparation method therefor | QILU PHARMACEUTICAL CO., LTD. (CN) | 2021-11-23 | — | — | US | disclosed |
| EP-3466950-B1 | NOVEL BETA-LACTAMASE INHIBITORS | QILU PHARMACEUTICAL CO LTD (CN) | 2021-02-24 | — | — | EP | disclosed |
| US-20200385385-A1 | CRYSTAL FORM OF ß-LACTAMASE INHIBITOR AND PREPARATION METHOD THEREFOR | QILU PHARMACEUTICAL CO., LTD. (CN) | 2020-12-10 | — | — | US | disclosed |
| EP-3719020-A1 | CRYSTAL FORM OF ß-LACTAMASE INHIBITOR AND PREPARATION METHOD THEREFOR | Qilu Pharmaceutical Co., Ltd (CN) | 2020-10-07 | — | — | EP | disclosed |
| US-10738051-B2 | β-lactamase inhibitors | QILU PHARMACEUTICAL CO., LTD. (CN) | 2020-08-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11180501-B2 | Crystal form of β-lactamase inhibitor and preparation method therefor | NOTUM, MRPL21, BPHL | GAA 43/4885ALDH1A1 1396/4885CYP1A2 882/4885 |
| US-20200385385-A1 | CRYSTAL FORM OF ß-LACTAMASE INHIBITOR AND PREPARATION METHOD THEREFOR | NOTUM, BPHL, DCXR | GAA 39/4885ALDH1A1 1283/4885CYP1A2 779/4885 |
| US-10738051-B2 | β-lactamase inhibitors | MGAM, LCT, CEL | GAA 11/4885ALDH1A1 494/4885CYP1A2 617/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.