Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | KISS1R | Q969F8 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | HRH1 | P35367 | 1/20 | 0.37 |
| ▸ | KDM4C | Q9H3R0 | 3/20 | 0.34 |
| ▸ | KDM4A | O75164 | 2/20 | 0.34 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.34 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.32 |
| ▸ | GRIA1 | P42261 | 3/20 | 0.32 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2042220 | 1.00 | EPHX1 (0.50) | EPHX1LMNAKISS1RSIGMAR1HTR2A | |
| SCHEMBL9947076 | 1.00 | EPHX1 (0.50) | EPHX1LMNAKISS1RSIGMAR1HTR2A | |
| SCHEMBL15346172 | 1.00 | EPHX1 (0.50) | EPHX1LMNAKISS1RSIGMAR1HTR2A | |
| SCHEMBL17104335 | 1.00 | EPHX1 (0.50) | EPHX1LMNAKISS1RSIGMAR1HTR2A | |
| SCHEMBL17104333 | 1.00 | EPHX1 (0.50) | EPHX1LMNAKISS1RSIGMAR1HTR2A | |
| SCHEMBL25122641 | 1.00 | EPHX1 (0.50) | EPHX1LMNAKISS1RSIGMAR1HTR2A | |
| SCHEMBL17104337 | 1.00 | EPHX1 (0.50) | EPHX1LMNAKISS1RSIGMAR1HTR2A | |
| SCHEMBL11213990 | 1.00 | EPHX1 (0.50) | EPHX1LMNAKISS1RSIGMAR1HTR2A | |
| SCHEMBL22564692 | 1.00 | EPHX1 (0.50) | EPHX1LMNAKISS1RSIGMAR1HTR2A | |
| SCHEMBL28266891 | 1.00 | EPHX1 (0.50) | EPHX1LMNAKISS1RSIGMAR1HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110669058-A | Tricyclic quinolone carboxylic acid and preparation method thereof | 江西农业大学 | 2020-01-10 | — | — | CN | claimed |
| US-11723980-B2 | IRAK degraders and uses thereof | KYMERA THERAPEUTICS, INC. (US) | 2023-08-15 | — | — | US | disclosed |
| EP-3356131-B1 | CLEANING PAD HAVING CORRELATED CLEANING PERFORMANCE | PROCTER & GAMBLE (US) | 2023-01-04 | — | — | EP | disclosed |
| WO-2022254362-A1 | 3-(1-OXOISOINDOLIN-2-YL)PIPERIDINE-2,6-DIONE DERIVATIVES AND MEDICAL USES THEREOF | NOVARTIS AG (CH) | 2022-12-08 | — | — | WO | disclosed |
| US-20210214316-A1 | ANTI-CANCER NUCLEAR HORMONE RECEPTOR-TARGETING COMPOUNDS | SAGARD HOLDINGS MANAGER LP, AS ADMINISTRATIVE AGENT (CA) | 2021-07-15 | — | — | US | disclosed |
| US-20210139771-A1 | Luminescent Compound | NATIONAL SCIENCE FOUNDATION | 2021-05-13 | — | — | US | disclosed |
| US-20200390901-A1 | CHEMOSELECTIVE THIOL-CONJUGATION WITH ALKENE OR ALKYNE-PHOSPHONOTHIOLATES AND - PHOSPHONATES | LUDWIG-MAXIMILIANS-UNIVERSITÄT MÜNCHEN (DE) | 2020-12-17 | — | — | US | disclosed |
| US-20200038513-A1 | MODULATORS OF FAK PROTEOLYSIS AND ASSOCIATED METHODS OF USE | YALE UNIVERSITY | 2020-02-06 | — | — | US | disclosed |
| CN-110669058-A | Tricyclic quinolone carboxylic acid and preparation method thereof | 江西农业大学 | 2020-01-10 | — | — | CN | disclosed |
| US-20190194390-A1 | AMINO-POLYESTERS FOR DRUG DELIVERY | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 2019-06-27 | — | — | US | disclosed |
| US-20080318159-A1 | POSITIVE PHOTOSENSITIVE COMPOSITION | FUJIFILM CORPORATION (JP) | 2008-12-25 | — | — | US | disclosed |
| US-20070141513-A1 | Positive photosensitive composition | FUJI PHOTO FILM CO., LTD. | 2007-06-21 | — | — | US | disclosed |
| US-7192681-B2 | Positive photosensitive composition | FUJI PHOTO FILM CO., LTD. (JP) | 2007-03-20 | — | — | US | disclosed |
| US-20030186161-A1 | Positive photosensitive composition | FUJI PHOTO FILM CO., LTD. | 2003-10-02 | — | — | US | disclosed |
| EP-1273970-A2 | Positive photosensitive composition | FUJI PHOTO FILM CO., LTD. (JP) | 2003-01-08 | — | — | EP | disclosed |
| EP-0031924-B1 | USE OF ALCANOL-AMINE SALTS OF CYCLIC AMIDOCARBOXYLIC ACIDS AS CORROSION INHIBITORS IN AQUEOUS SYSTEMS | BASF Aktiengesellschaft (DE) | 1983-05-18 | — | — | EP | disclosed |
| US-4352696-A | Process and composition | THE UPJOHN COMPANY (US) | 1982-10-05 | — | — | US | disclosed |
| EP-0031924-A1 | Use of alcanol-amine salts of cyclic amidocarboxylic acids as corrosion inhibitors in aqueous systems | BASF Aktiengesellschaft (DE) | 1981-07-15 | — | — | EP | disclosed |
| US-4257995-A | STORAGE STABILITY | THE UPJOHN COMPANY (US) | 1981-03-24 | — | — | US | disclosed |
| US-3957698-A | Thermally reversible, amphoteric ion exchange resins consisting of crosslinked microbeads embedded in crosslinked matrix of opposite exchange group type | THE DOW CHEMICAL COMPANY (US) | 1976-05-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200390901-A1 | CHEMOSELECTIVE THIOL-CONJUGATION WITH ALKENE OR ALKYNE-PHOSPHONOTHIOLATES AND - PHOSPHONATES | ACP1, PTMS, ALG1 | EPHX1 3960/4885LMNA 4559/4885KISS1R 3716/4885 |
| US-20210214316-A1 | ANTI-CANCER NUCLEAR HORMONE RECEPTOR-TARGETING COMPOUNDS | NCOA1, NCOR1, NCOA3 | EPHX1 4120/4885LMNA 2220/4885KISS1R 1022/4885 |
| US-11723980-B2 | IRAK degraders and uses thereof | IRAK2, IRAK3, IRAK1 | EPHX1 1684/4885LMNA 1656/4885KISS1R 2435/4885 |
| US-20200038513-A1 | MODULATORS OF FAK PROTEOLYSIS AND ASSOCIATED METHODS OF USE | PTK2, CTTN, CRBN | EPHX1 2806/4885LMNA 2521/4885KISS1R 4708/4885 |
| US-20190194390-A1 | AMINO-POLYESTERS FOR DRUG DELIVERY | DNPEP, NPEPPS, ANPEP | EPHX1 2020/4885LMNA 2232/4885KISS1R 3408/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.