SCHEMBL1508395

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1508341	0.79	FFAR1 (0.47)	FFAR1
	SCHEMBL11123838	0.74	ESR1 (0.45)	ESR1LMNACYP1A2PGRCHRM2
	SCHEMBL2836885	0.72	ESR1 (0.47)	ESR1LMNACYP1A2PGRCHRM2
	SCHEMBL29183695	0.69	ESR1 (0.46)	ESR1LMNACHRM2CYP3A4ADORA3
	SCHEMBL9576635	0.69	ESR1 (0.55)	ESR1LMNACYP1A2PGRCHRM2
	SCHEMBL2219321	0.68	ESR1 (0.50)	ESR1LMNACYP1A2PGRCHRM2
	SCHEMBL4031828	0.67	FFAR1 (0.62)	FFAR1
	SCHEMBL10316924	0.67	FFAR1 (0.62)	FFAR1
	SCHEMBL9889127	0.67	TAAR1 (0.45)	ESR1LMNACHRM2CYP3A4ADORA3
	SCHEMBL18609118	0.66	ESR1 (0.52)	ESR1LMNACYP1A2PGRCHRM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.