SCHEMBL15084239

SCHEMBL15084239

CC1(O)NCc2ccccc21

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.41
MAPT P10636 1/20 0.41
CYP3A4 P08684 2/20 0.40
MEN1 O00255 1/20 0.40
CYP2D6 P10635 1/20 0.40
ALOX15 P16050 1/20 0.40
CYP2C19 P33261 1/20 0.40
KMT2A Q03164 1/20 0.40
GRIN2D O15399 1/20 0.40
GRIN3B O60391 1/20 0.40
BCHE P06276 1/20 0.40
CHRM5 P08912 1/20 0.40
TSHR P16473 1/20 0.40
ALOX12 P18054 1/20 0.40
NFKB1 P19838 1/20 0.40
MAPK1 P28482 1/20 0.40
PRCP P42785 1/20 0.40
GRIN1 Q05586 1/20 0.40
GRIN2A Q12879 1/20 0.40
GRIN2B Q13224 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3542185 0.78 ALDH1A1 (0.43) ALDH1A1MAPTCYP3A4MEN1CYP2D6
SCHEMBL5179163 0.78 CHRM2 (0.38) CHRM5MAPK1
SCHEMBL28027267 0.75 ALDH1A1 (0.41) ALDH1A1MAPTCYP3A4MEN1CYP2D6
SCHEMBL3696570 0.73 ALDH1A1 (0.44) ALDH1A1MAPTCYP3A4ALOX12HSD17B10
SCHEMBL24317231 0.72 ALDH1A1 (0.39) ALDH1A1MAPTCYP3A4MEN1CYP2D6
SCHEMBL29569241 0.72 GAA (0.35)
SCHEMBL20399183 0.72 ALDH1A1 (0.39) ALDH1A1MAPTCYP3A4MEN1CYP2D6
SCHEMBL28205886 0.72 HTR2A (0.37) ALDH1A1MAPTCYP3A4MEN1CYP2D6
SCHEMBL27945208 0.71 ALDH1A1 (0.38) ALDH1A1MAPTCYP3A4MEN1CYP2D6
SCHEMBL24224352 0.71 ALDH1A1 (0.38) ALDH1A1MAPTCYP3A4MEN1CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2013098833-A2 PROCESSES AND INTERMEDIATES FOR PREPARING RIVAROXABAN CADILA HEALTHCARE LIMITED (IN) 2013-07-04 WO disclosed