Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.53 |
| ▸ | TFEB | P19484 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.50 |
| ▸ | MAOB | P27338 | 6/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | BCHE | P06276 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | LY96 | Q9Y6Y9 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1508460 | 1.00 | NFE2L2 (0.53) | NFE2L2TFEBKDM4EMAOBMAPT | |
| SCHEMBL19244242 | 0.86 | NFE2L2 (0.54) | NFE2L2TFEBKDM4EMAOBMAPT | |
| SCHEMBL19244243 | 0.86 | NFE2L2 (0.54) | NFE2L2TFEBKDM4EMAOBMAPT | |
| SCHEMBL24728219 | 0.84 | KDM4E (0.66) | NFE2L2TFEBKDM4EMAOBMAPT | |
| SCHEMBL7631196 | 0.84 | KDM4E (0.66) | NFE2L2TFEBKDM4EMAOBMAPT | |
| SCHEMBL4086751 | 0.84 | KDM4E (0.49) | NFE2L2TFEBKDM4EMAOBMAPT | |
| SCHEMBL4086754 | 0.84 | KDM4E (0.49) | NFE2L2TFEBKDM4EMAOBMAPT | |
| SCHEMBL28550579 | 0.84 | MAOB (0.65) | NFE2L2TFEBKDM4EMAOBMAPT | |
| SCHEMBL11004162 | 0.83 | NFE2L2 (0.62) | NFE2L2TFEBKDM4EMAOBMAPT | |
| SCHEMBL1536410 | 0.83 | HTT (0.61) | NFE2L2TFEBKDM4EMAOBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2289868-A1 | CARBOXYLIC ACID COMPOUND | Daiichi Sankyo Company, Limited (JP) | 2011-03-02 | — | — | EP | disclosed |