Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 20/20 | 0.53 |
| ▸ | PDE4B | Q07343 | 20/20 | 0.53 |
| ▸ | PDE4C | Q08493 | 20/20 | 0.53 |
| ▸ | PDE4D | Q08499 | 20/20 | 0.53 |
| ▸ | PDE3B | Q13370 | 20/20 | 0.53 |
| ▸ | PDE3A | Q14432 | 20/20 | 0.53 |
| ▸ | PDE5A | O76074 | 19/20 | 0.53 |
| ▸ | PDE1A | P54750 | 14/20 | 0.39 |
| ▸ | PDE1B | Q01064 | 14/20 | 0.39 |
| ▸ | PDE1C | Q14123 | 14/20 | 0.39 |
| ▸ | PDE2A | O00408 | 2/20 | 0.37 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.37 |
| ▸ | PDE7B | Q9NP56 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL155132 | 0.86 | PDE4A (0.70) | PDE4APDE4BPDE4CPDE4DPDE3B | |
| SCHEMBL29623702 | 0.86 | PDE4A (0.70) | PDE4APDE4BPDE4CPDE4DPDE3B | |
| SCHEMBL7285109 | 0.83 | PDE4A (0.75) | PDE4APDE4BPDE4CPDE4DPDE3B | |
| SCHEMBL2473235 | 0.78 | PDE4A (0.71) | PDE4APDE4BPDE4CPDE4DPDE3B | |
| SCHEMBL15085278 | 0.77 | PDE5A (0.57) | PDE4APDE4BPDE4CPDE4DPDE3B | |
| SCHEMBL7289581 | 0.74 | PDE4A (0.60) | PDE4APDE4BPDE4CPDE4DPDE3B | |
| SCHEMBL12013957 | 0.73 | PDE4A (0.60) | PDE4APDE4BPDE4CPDE4DPDE3B | |
| SCHEMBL7287261 | 0.70 | PDE4A (1.00) | PDE4APDE4BPDE4CPDE4DPDE3B | |
| SCHEMBL7285598 | 0.68 | PDE4A (0.76) | PDE4APDE4BPDE4CPDE4DPDE3B | |
| SCHEMBL7279127 | 0.66 | PDE4A (0.74) | PDE4APDE4BPDE4CPDE4DPDE3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1389467-B1 | Therapeutic composition for the regenerative treatment of cartilage diseases | MITSUBISHI TANABE PHARMA CORP (JP) | 2013-07-03 | — | — | EP | disclosed |