SCHEMBL15085584

SCHEMBL15085584

Cc1ccc(S(=O)(=O)O)c(C2=NN(c3ncccc3Cl)C(C(=O)Nc3ccc(Cl)cc3C(=O)NC(C)C3CC3)C2)c1

nearest known ligand 0.36

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
F10 P00742 1/20 0.36
EPHX2 P34913 4/20 0.35
TP53 P04637 1/20 0.34
THRB P10828 1/20 0.34
MALT1 Q9UDY8 2/20 0.34
IDO1 P14902 3/20 0.33
NPC1 O15118 1/20 0.33
RAB9A P51151 1/20 0.33
CCR8 P51685 2/20 0.33
SLC6A9 P48067 1/20 0.32
NAMPT P43490 2/20 0.32
PPARD Q03181 1/20 0.32
TRPV1 Q8NER1 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1147804 0.91 ALDH1A1 (0.34) F10TP53MALT1IDO1NPC1
SCHEMBL15085552 0.90 F10 (0.37) F10TP53THRBMALT1IDO1
SCHEMBL15085594 0.90 F10 (0.37) F10MALT1IDO1NPC1RAB9A
SCHEMBL15085595 0.87 F10 (0.34) F10TP53THRBMALT1IDO1
SCHEMBL15085600 0.86 F10 (0.37) F10MALT1IDO1NPC1RAB9A
SCHEMBL15085565 0.86 F10 (0.34) F10TP53THRBMALT1IDO1
SCHEMBL590447 0.84 F10 (0.41) F10MALT1IDO1NPC1RAB9A
SCHEMBL590692 0.84 F10 (0.37) F10TP53THRBMALT1IDO1
SCHEMBL589790 0.83 F10 (0.41) F10MALT1IDO1NPC1RAB9A
SCHEMBL15085562 0.82 MALT1 (0.34) EPHX2MALT1IDO1NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8481744-B2 Process for producing anthranilamide compound ISHIHARA SANGYO KAISHA, LTD. (JP) 2013-07-09 US disclosed