SCHEMBL1508564

SCHEMBL1508564

CCOC(=O)CC(OCC)c1ccc(OCc2ccccc2C)cc1

nearest known ligand 0.80

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 19/20 0.80
MAOB P27338 1/20 0.52
PPARG P37231 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1508359 0.89 FFAR1 (1.00) FFAR1PPARG
SCHEMBL1508528 0.85 FFAR1 (0.62) FFAR1MAOB
SCHEMBL13118044 0.81 FFAR1 (0.59) FFAR1MAOB
SCHEMBL3821109 0.79 FFAR1 (0.51) FFAR1
SCHEMBL1508413 0.78 FFAR1 (0.82) FFAR1PPARG
SCHEMBL1508345 0.78 FFAR1 (0.49) FFAR1PPARG
SCHEMBL1537722 0.77 FFAR1 (0.66) FFAR1PPARG
SCHEMBL1508019 0.76 FFAR1 (0.80) FFAR1MAOBPPARG
SCHEMBL1508523 0.76 FFAR1 (0.80) FFAR1
SCHEMBL1508498 0.76 FFAR1 (0.62) FFAR1PPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8222281-B2 Carboxylic acid compound DAIICHI SANKYO COMPANY, LIMITED (JP) 2012-07-17 US disclosed
US-20110053974-A1 CARBOXYLIC ACID COMPOUND DAIICHI SANKYO COMPANY, LIMITED (JP) 2011-03-03 US disclosed
EP-2289868-A1 CARBOXYLIC ACID COMPOUND Daiichi Sankyo Company, Limited (JP) 2011-03-02 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110053974-A1 CARBOXYLIC ACID COMPOUND AKR1C3, SLC5A1, GPR119 FFAR1 219/4885MAOB 904/4885PPARG 200/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.