Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15085664 | 1.00 | NAE1 (0.40) | NAE1UBA3 | |
| SCHEMBL782681 | 0.91 | NAE1 (0.41) | NAE1UBA3 | |
| SCHEMBL782949 | 0.91 | NAE1 (0.41) | NAE1UBA3 | |
| SCHEMBL783026 | 0.91 | NAE1 (0.41) | NAE1UBA3 | |
| SCHEMBL782682 | 0.91 | NAE1 (0.41) | NAE1UBA3 | |
| SCHEMBL783671 | 0.72 | NAE1 (0.57) | NAE1UBA3 | |
| SCHEMBL782789 | 0.72 | NAE1 (0.57) | NAE1UBA3 | |
| SCHEMBL782852 | 0.66 | NAE1 (0.46) | NAE1UBA3 | |
| SCHEMBL2879225 | 0.66 | NAE1 (0.46) | NAE1UBA3 | |
| SCHEMBL782811 | 0.64 | NAE1 (0.56) | NAE1UBA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8481550-B2 | Heteroaryl compounds useful as inhibitors of E1 activating enzymes | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2013-07-09 | — | — | US | disclosed |