Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XIAP | P98170 | 12/20 | 0.45 |
| ▸ | BIRC3 | Q13489 | 6/20 | 0.45 |
| ▸ | BIRC2 | Q13490 | 11/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2114710 | 1.00 | XIAP (0.45) | XIAPBIRC3BIRC2 | |
| SCHEMBL2117128 | 1.00 | XIAP (0.45) | XIAPBIRC3BIRC2 | |
| SCHEMBL2632164 | 1.00 | XIAP (0.45) | XIAPBIRC3BIRC2 | |
| SCHEMBL2631838 | 0.92 | XIAP (0.46) | XIAPBIRC3BIRC2 | |
| SCHEMBL2115283 | 0.92 | XIAP (0.46) | XIAPBIRC3BIRC2 | |
| SCHEMBL2632166 | 0.88 | XIAP (0.48) | XIAPBIRC3BIRC2 | |
| SCHEMBL2114003 | 0.88 | XIAP (0.48) | XIAPBIRC3BIRC2 | |
| SCHEMBL2115381 | 0.87 | XIAP (0.44) | XIAPBIRC3BIRC2 | |
| SCHEMBL2632126 | 0.87 | XIAP (0.44) | XIAPBIRC3BIRC2 | |
| SCHEMBL10284304 | 0.86 | XIAP (0.51) | XIAPBIRC3BIRC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150344467-A1 | 5- AND 6-MEMBERED HETEROCYCLIC COMPOUNDS | FMR LLC | 2015-12-03 | — | — | US | disclosed |
| US-20140038965-A1 | 5- AND 6-MEMBERED HETEROCYCLIC COMPOUNDS | ENVIVO PHARMACEUTICALS, INC. (US) | 2014-02-06 | — | — | US | disclosed |
| US-8481534-B2 | 5- and 6-membered heterocyclic compounds | ENVIVO PHARMACEUTICALS, INC. (US) | 2013-07-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150344467-A1 | 5- AND 6-MEMBERED HETEROCYCLIC COMPOUNDS | PDE7A, ACHE, PDE5A | XIAP 2565/4885BIRC3 2774/4885BIRC2 2922/4885 |
| US-20140038965-A1 | 5- AND 6-MEMBERED HETEROCYCLIC COMPOUNDS | PDE7A, ACHE, PDE5A | XIAP 2565/4885BIRC3 2774/4885BIRC2 2922/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.