Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 2/20 | 0.40 |
| ▸ | CNR2 | P34972 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.33 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.32 |
| ▸ | APP | P05067 | 1/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.30 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.30 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15087322 | 0.97 | TP53 (0.41) | CNR1CNR2TP53TDP1HSD17B1 | |
| SCHEMBL12757056 | 0.91 | TDP1 (0.47) | TP53TDP1HSD17B1HSD17B2CYP3A4 | |
| SCHEMBL766100 | 0.91 | TDP1 (0.47) | TP53TDP1HSD17B1HSD17B2CYP3A4 | |
| SCHEMBL15087293 | 0.88 | ALDH1A1 (0.38) | CNR1CNR2TP53TDP1CYP3A4 | |
| SCHEMBL15087336 | 0.88 | ALDH1A1 (0.38) | CNR1CNR2TP53TDP1CYP3A4 | |
| SCHEMBL2602506 | 0.88 | TDP1 (0.50) | TP53TDP1HSD17B1HSD17B2ALDH1A1 | |
| SCHEMBL19668947 | 0.87 | TDP1 (0.44) | TP53TDP1HSD17B1HSD17B2CYP3A4 | |
| SCHEMBL19244062 | 0.87 | TDP1 (0.52) | TP53TDP1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL12909791 | 0.87 | TDP1 (0.52) | TP53TDP1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL5843443 | 0.87 | TDP1 (0.52) | TP53TDP1CYP3A4CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2797871-B1 | CROSSLINKABLE ARYLAMINE COMPOUNDS | NISSAN CHEMICAL IND LTD (JP) | 2018-05-09 | — | — | EP | disclosed |
| US-20150094437-A1 | CROSSLINKABLE ARYLAMINE COMPOUNDS | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2015-04-02 | — | — | US | disclosed |
| US-20150094437-A1 | CROSSLINKABLE ARYLAMINE COMPOUNDS | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2015-04-02 | — | — | US | disclosed |
| WO-2013098175-A1 | CROSSLINKABLE ARYLAMINE COMPOUNDS | SOLVAY SA (BE) | 2013-07-04 | — | — | WO | disclosed |
| EP-2610240-A1 | Crosslinkable arylamine compounds | SOLVAY SA (BE) | 2013-07-03 | — | — | EP | disclosed |