SCHEMBL1508738

SCHEMBL1508738

Cc1c(OOC(C)(C)C)cccc1C(=O)O

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGER1 P34995 1/20 0.43
TSHR P16473 4/20 0.42
MAPK1 P28482 1/20 0.42
KDM4E B2RXH2 6/20 0.42
HSD17B10 Q99714 6/20 0.42
HPGD P15428 5/20 0.42
ALDH1A1 P00352 5/20 0.42
TDP1 Q9NUW8 2/20 0.42
ESR1 P03372 1/20 0.42
ITGB3 P05106 1/20 0.42
ITGA2B P08514 1/20 0.42
HMGB1 P09429 1/20 0.42
GGT1 P19440 1/20 0.42
PTGS1 P23219 1/20 0.42
PTGS2 P35354 1/20 0.42
BLM P54132 1/20 0.42
NAPRT Q6XQN6 1/20 0.42
ALOX15 P16050 1/20 0.41
HTT P42858 2/20 0.40
TLR2 O60603 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28567814 0.85 TSHR (0.41) TSHRKDM4EHSD17B10ALDH1A1TDP1
SCHEMBL17273601 0.85 TSHR (0.38) TSHRKDM4EHSD17B10ALDH1A1TDP1
SCHEMBL9850286 0.84 PTGER1 (0.43) PTGER1TSHRMAPK1KDM4EHSD17B10
SCHEMBL153852 0.84 KDM4E (0.55) TSHRMAPK1KDM4EHSD17B10HPGD
SCHEMBL10934705 0.83 HSD17B10 (0.49) TSHRMAPK1KDM4EHSD17B10HPGD
SCHEMBL346597 0.83 MAPK1 (0.50) TSHRMAPK1KDM4EHSD17B10HPGD
SCHEMBL2477856 0.83 CA12 (0.46) TSHRMAPK1KDM4EHSD17B10HPGD
SCHEMBL5227296 0.83 PTGER1 (0.46) PTGER1TSHRMAPK1KDM4EHSD17B10
SCHEMBL9067284 0.82 PTGER1 (0.41) PTGER1TSHRMAPK1KDM4EHSD17B10
SCHEMBL27515327 0.81 KDM4E (0.41) TSHRMAPK1KDM4EHSD17B10HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9550731-B2 Method for phase transfer synthesis of organic peroxides HONEYWELL FEDERAL MANUFACTURING & TECHNOLOGIES, LLC (US) 2017-01-24 US claimed
EP-1440097-B1 HIGH INDEX CURABLE PHOTOCHROMIC COMPOSITION AND ITS PROCESS RODENSTOCK GMBH (DE) 2008-03-12 EP claimed
EP-0084715-B1 A PROCESS FOR PREPARING POLY(P-METHYLSTYRENE) MOBIL OIL CORPORATION (US) 1986-10-22 EP claimed
JP-57092005-A None JP disclosed
CN-117165133-A Preparation method of high-temperature-resistant aqueous anticorrosive paint 互邦科技保定有限公司 2023-12-05 CN disclosed
CN-113924282-A Process for separating carboxylic acids from aqueous sidestreams 诺力昂化学品国际有限公司 2022-01-11 CN disclosed
CN-111164152-A Process for producing thermoplastic resin 帝斯曼知识产权资产管理有限公司 2020-05-15 CN disclosed
EP-2766444-B1 GEL TIME CONTROLLABLE TWO PART EPOXY ADHESIVE HENKEL AG & CO KGAA (DE) 2017-06-28 EP disclosed
US-9550731-B2 Method for phase transfer synthesis of organic peroxides HONEYWELL FEDERAL MANUFACTURING & TECHNOLOGIES, LLC (US) 2017-01-24 US disclosed
US-9371475-B2 Gel time controllable two part epoxy adhesive Henkel IP & Holding GmbH (DE) 2016-06-21 US disclosed
US-20150336886-A1 METHOD FOR PHASE TRANSFER SYNTHESIS OF ORGANIC PEROXIDES HONEYWELL FEDERAL MANUFACTURING & TECHNOLOGIES, LLC 2015-11-26 US disclosed
EP-1882199-A1 METHOD FOR PRODUCING A PHOTOCHROMIC PLASTIC ARTICLE Rodenstock GmbH (DE) 2008-01-30 EP disclosed
WO-2006122795-A1 METHOD FOR PRODUCING A PHOTOCHROMIC PLASTIC ARTICLE RODENSTOCK GMBH (DE) 2006-11-23 WO disclosed
US-6433037-B1 ACRYLIC RESIN ABSORBS FREE-RADICAL POLYMERIZABLE UNSATURATED MONOMER, OLIGOMER, OR POLYMER AND MATURES INTO MOLDABLE DOUGH; DENTISTRY, AUTOMOBILES, BATHROOM FIXTURES; LOW TEMPERATURE AND PRESSURE REINFORCED POLYMERS, INC. 2002-08-13 US disclosed
US-6103779-A MIXING SOLID ACRYLIC RESIN WITH ONE OR MORE LIQUID UNSATURATED MONOMERS, OLIGOMERS OR POLYMERS AND INSOLUBLE LONG FIBER REINFORCEMENT, AGING MIXTURE TO ALLOW SOLID RESIN TO ABSORB LIQUID REINFORCED POLMERS, INC. (US) 2000-08-15 US disclosed
EP-0346863-B1 Mixture suited for the cross-linking of polymers, and process for the cross-linking of polymers with extended scorch time ATOCHEM ELF DEUTSCHLAND (DE) 1993-12-29 EP disclosed
EP-0180789-B1 CROSS-LINKING OF STYRENE POLYMERS Luperox GmbH (DE) 1990-02-28 EP disclosed
EP-0346863-A1 Mixture suited for the cross-linking of polymers, and process for the cross-linking of polymers with extended scorch time Elf Atochem Deutschland GmbH (DE) 1989-12-20 EP disclosed
EP-0180789-A1 Cross-linking of styrene polymers Luperox GmbH (DE) 1986-05-14 EP disclosed
JP-S5792005-A PEROXY ESTER COMPOSITION NIPPON OIL & FATS CO LTD 1982-06-08 JP disclosed