SCHEMBL1508845

SCHEMBL1508845

O=C(CCCCCCCCCCS)ON1C(=O)CCC1=O

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.38
KMT2A Q03164 1/20 0.38
HDAC3 O15379 7/20 0.37
HDAC1 Q13547 7/20 0.37
HDAC10 Q969S8 7/20 0.37
HDAC11 Q96DB2 7/20 0.37
FOLH1 Q04609 1/20 0.36
HDAC2 Q92769 6/20 0.33
HDAC8 Q9BY41 6/20 0.33
HDAC6 Q9UBN7 6/20 0.33
HPGD P15428 1/20 0.33
HTT P42858 1/20 0.33
HDAC4 P56524 5/20 0.33
HDAC7 Q8WUI4 5/20 0.33
HDAC9 Q9UKV0 5/20 0.33
HDAC5 Q9UQL6 5/20 0.33
ALDH1A1 P00352 1/20 0.31
GAA P10253 1/20 0.31
PSMB8 P28062 1/20 0.31
PSMB5 P28074 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28630993 1.00 SMN1; SMN2 (0.38) SMN1; SMN2KMT2AHDAC3HDAC1HDAC10
SCHEMBL18170352 1.00 SMN1; SMN2 (0.38) SMN1; SMN2KMT2AHDAC3HDAC1HDAC10
SCHEMBL13257737 0.93 KMT2A (0.33) SMN1; SMN2KMT2AFOLH1PSMB8PSMB5
SCHEMBL37833 0.91 SMN1; SMN2 (0.42) SMN1; SMN2KMT2AHPGDHTTALDH1A1
SCHEMBL905404 0.91 SMN1; SMN2 (0.42) SMN1; SMN2KMT2AHPGDHTTALDH1A1
SCHEMBL1870550 0.91 SMN1; SMN2 (0.42) SMN1; SMN2KMT2AHPGDHTTALDH1A1
SCHEMBL905722 0.91 SMN1; SMN2 (0.42) SMN1; SMN2KMT2AHPGDHTTALDH1A1
SCHEMBL4960230 0.91 SMN1; SMN2 (0.42) SMN1; SMN2KMT2AHPGDHTTALDH1A1
SCHEMBL16983769 0.91 SMN1; SMN2 (0.42) SMN1; SMN2KMT2AHPGDHTTALDH1A1
SCHEMBL905700 0.91 SMN1; SMN2 (0.42) SMN1; SMN2KMT2AHPGDHTTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109541218-B Method for identifying silk fabric fragments based on enzyme-linked immunosorbent assay 浙江理工大学 2022-07-12 CN disclosed
EP-2288348-A1 NANOPARTICLES FUNCTIONALIZED WITH SULFATED AMINO ALCOHOLS FOR THE INHIBITION OF SELECTIN-MEDIATED CELL ADHESION Freie Universität Berlin (DE) 2011-03-02 EP disclosed
EP-2197494-A2 FUNCTIONALIZED NANOPARTICLES FOR THE INHIBITION OF SELECTIN-MEDIATED CELL ADHESION Freie Universität Berlin (DE) 2010-06-23 EP disclosed
WO-2009141142-A1 NANOPARTICLES FUNCTIONALIZED WITH SULFATED AMINO ALCOHOLS FOR THE INHIBITION OF SELECTIN-MEDIATED CELL ADHESION FREIE UNIVERSITÄT BERLIN (DE) 2009-11-26 WO disclosed
EP-2123269-A1 Nanoparticles functionalized with sulfated amino alcohols for the inhibition of selectin-mediated cell adhesion Freie Universität Berlin (DE) 2009-11-25 EP disclosed
WO-2009030492-A2 FUNCTIONALIZED NANOPARTICLES FOR THE INHIBITION OF SELECTIN-MEDIATED CELL ADHESION FREIE UNIVERSITÄT BERLIN (DE) 2009-03-12 WO disclosed
EP-2033660-A1 Functionalized nanoparticles for the inhibition of selectin-mediated cell adhesion Freie Universität Berlin (DE) 2009-03-11 EP disclosed
US-20090047695-A1 MICRODEVICES FOR HIGH-THROUGHPUT SCREENING OF BIOMOLECULES ZYOMYX, INC. (US) 2009-02-19 US disclosed