SCHEMBL18170352

SCHEMBL18170352

O=C(CCCCCCCCCCCS)ON1C(=O)CCC1=O

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.38
KMT2A Q03164 1/20 0.38
HDAC3 O15379 7/20 0.37
HDAC1 Q13547 7/20 0.37
HDAC10 Q969S8 7/20 0.37
HDAC11 Q96DB2 7/20 0.37
FOLH1 Q04609 1/20 0.36
HDAC2 Q92769 6/20 0.33
HDAC8 Q9BY41 6/20 0.33
HDAC6 Q9UBN7 6/20 0.33
HPGD P15428 1/20 0.33
HTT P42858 1/20 0.33
HDAC4 P56524 5/20 0.33
HDAC7 Q8WUI4 5/20 0.33
HDAC9 Q9UKV0 5/20 0.33
HDAC5 Q9UQL6 5/20 0.33
ALDH1A1 P00352 1/20 0.31
GAA P10253 1/20 0.31
PSMB8 P28062 1/20 0.31
PSMB5 P28074 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28630993 1.00 SMN1; SMN2 (0.38) SMN1; SMN2KMT2AHDAC3HDAC1HDAC10
SCHEMBL1508845 1.00 SMN1; SMN2 (0.38) SMN1; SMN2KMT2AHDAC3HDAC1HDAC10
SCHEMBL13257737 0.93 KMT2A (0.33) SMN1; SMN2KMT2AFOLH1PSMB8PSMB5
SCHEMBL37833 0.91 SMN1; SMN2 (0.42) SMN1; SMN2KMT2AHPGDHTTALDH1A1
SCHEMBL905404 0.91 SMN1; SMN2 (0.42) SMN1; SMN2KMT2AHPGDHTTALDH1A1
SCHEMBL1870550 0.91 SMN1; SMN2 (0.42) SMN1; SMN2KMT2AHPGDHTTALDH1A1
SCHEMBL905722 0.91 SMN1; SMN2 (0.42) SMN1; SMN2KMT2AHPGDHTTALDH1A1
SCHEMBL4960230 0.91 SMN1; SMN2 (0.42) SMN1; SMN2KMT2AHPGDHTTALDH1A1
SCHEMBL16983769 0.91 SMN1; SMN2 (0.42) SMN1; SMN2KMT2AHPGDHTTALDH1A1
SCHEMBL905700 0.91 SMN1; SMN2 (0.42) SMN1; SMN2KMT2AHPGDHTTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230132381-A9 SYNTHESIS OF FUNCTIONALIZABLE OR FUNCTIONALIZED POLY(3,4-ETHYLENEDIOXYTHIPHENE)-BASED POLYMERS AND MONOMERS THEREFOR PITTSBURGH, UNIVERSITY OF - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION 2023-04-27 US claimed
US-20250052675-A1 Attenuated Total Reflectance-Based Biosensor for Conformation and Secondary Structure Analysis BETASENSE GMBH (DE) 2025-02-13 US disclosed
EP-3305853-B1 DISPERSION ASAHI CHEMICAL IND (JP) 2024-07-10 EP disclosed
US-20240201198-A1 COMPOSITIONS, METHODS, AND UTILITY OF CONJUGATED BIOMOLECULE BARCODES BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM 2024-06-20 US disclosed
EP-3631446-B1 BIOSENSOR FOR CONFORMATION AND SECONDARY STRUCTURE ANALYSIS BETASENSE GMBH (DE) 2024-04-17 EP disclosed
EP-4348267-A2 COMPOSITIONS, METHODS, AND UTILITY OF CONJUGATED BIOMOLECULE BARCODES Board of Regents, The University of Texas System (US) 2024-04-10 EP disclosed
US-20230132381-A9 SYNTHESIS OF FUNCTIONALIZABLE OR FUNCTIONALIZED POLY(3,4-ETHYLENEDIOXYTHIPHENE)-BASED POLYMERS AND MONOMERS THEREFOR PITTSBURGH, UNIVERSITY OF - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION 2023-04-27 US disclosed
WO-2022251457-A2 COMPOSITIONS, METHODS, AND UTILITY OF CONJUGATED BIOMOLECULE BARCODES BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2022-12-01 WO disclosed
US-11237176-B2 Infrared assay detecting secondary structure profiles of alpha-synuclein PROTHENA BIOSCIENCES LIMITED (IE) 2022-02-01 US disclosed
EP-3943942-A1 BIOSENSOR FOR CONFORMATION AND SECONDARY STRUCTURE ANALYSIS betaSENSE GmbH (DE) 2022-01-26 EP disclosed
US-20160313313-A1 LATERAL FLOW ASSAY APPARATUS AND METHOD, AND SENSOR THERFOR THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO (CA) 2016-10-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230132381-A9 SYNTHESIS OF FUNCTIONALIZABLE OR FUNCTIONALIZED POLY(3,4-ETHYLENEDIOXYTHIPHENE)-BASED POLYMERS AND MONOMERS THEREFOR SLC6A11, KCNT1, SLC39A11 SMN1; SMN2 4768/4885KMT2A 593/4885HDAC3 1014/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.