SCHEMBL15088807

SCHEMBL15088807

Cc1cccc(N2c3cc4c(cc3-c3cccc5cccc2c35)c2ccccc2n4-c2ccccc2)c1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 4/20 0.40
KDM4E B2RXH2 3/20 0.40
ATM Q13315 1/20 0.40
MEN1 O00255 5/20 0.37
KMT2A Q03164 5/20 0.37
USP2 O75604 2/20 0.37
KEAP1 Q14145 2/20 0.37
NFE2L2 Q16236 2/20 0.37
RXFP1 Q9HBX9 1/20 0.36
PDE6D O43924 1/20 0.35
PDE10A Q9Y233 1/20 0.35
GAA P10253 2/20 0.34
CASP6 P55212 1/20 0.34
MAPT P10636 3/20 0.33
NPSR1 Q6W5P4 1/20 0.33
MCL1 Q07820 1/20 0.33
BAD Q92934 1/20 0.33
LMNA P02545 2/20 0.33
HSP90AA1 P07900 1/20 0.33
MGLL Q99685 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15088835 0.97 MEN1 (0.38) L3MBTL1KDM4EATMMEN1KMT2A
SCHEMBL15088864 0.96 MEN1 (0.37) L3MBTL1KDM4EATMMEN1KMT2A
SCHEMBL15088810 0.93 L3MBTL1 (0.40) L3MBTL1KDM4EATMMEN1KMT2A
SCHEMBL15089112 0.91 L3MBTL1 (0.44) L3MBTL1KDM4EATMMEN1KMT2A
SCHEMBL15088905 0.91 L3MBTL1 (0.46) L3MBTL1KDM4EATMMEN1KMT2A
SCHEMBL15089127 0.90 L3MBTL1 (0.45) L3MBTL1KDM4EATMMEN1KMT2A
SCHEMBL15088808 0.89 PDE6D (0.42) L3MBTL1MEN1KMT2AUSP2KEAP1
SCHEMBL15088809 0.89 PDE6D (0.34) L3MBTL1KDM4EATMMEN1KMT2A
SCHEMBL15088923 0.88 L3MBTL1 (0.39) L3MBTL1KDM4EATMMEN1KMT2A
SCHEMBL15089126 0.88 PDE6D (0.43) L3MBTL1KDM4EATMMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2013100497-A1 ORGANIC LIGHT-EMITTING COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE USING SAME 주식회사 두산 (KR) 2013-07-04 WO disclosed