SCHEMBL15088902

SCHEMBL15088902

c1ccc(-c2ccc3c(c2)c2cc4c(cc2n3-c2cc(-c3cccnc3)cc(-c3cccnc3)n2)N(c2cc(-c3cccnc3)cc(-c3cccnc3)n2)c2cccc3c(-c5ccccc5)ccc-4c23)cc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 2/20 0.39
DHODH Q02127 1/20 0.36
PIK3CA P42336 1/20 0.34
HDAC8 Q9BY41 1/20 0.33
CYP2C9 P11712 1/20 0.32
CYP11B1 P15538 3/20 0.32
CYP11B2 P19099 3/20 0.32
PRKDC P78527 1/20 0.32
MAPK14 Q16539 1/20 0.32
ALDH1A1 P00352 1/20 0.31
NR4A2 P43354 1/20 0.31
CYP17A1 P05093 1/20 0.31
KDM4E B2RXH2 1/20 0.31
LMNA P02545 1/20 0.31
HTT P42858 1/20 0.31
PLAUR Q03405 1/20 0.31
NTSR1 P30989 1/20 0.31
MAPT P10636 1/20 0.30
PGR P06401 1/20 0.30
G6PD P11413 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15088820 0.91 KDM4E (0.30) ALDH1A1KDM4EPLAURMAPT
SCHEMBL15088797 0.91 CYP19A1 (0.40) CYP19A1DHODHPIK3CAHDAC8CYP2C9
SCHEMBL15088895 0.89 CYP2A6 (0.35) CYP19A1DHODHPRKDCPLAURMAPT
SCHEMBL15088926 0.89 PIK3CA (0.40) CYP19A1PIK3CACYP11B1CYP11B2PRKDC
SCHEMBL15088834 0.87 PIK3CA (0.37) CYP19A1DHODHPIK3CACYP11B1CYP11B2
SCHEMBL15088872 0.86 PDE6D (0.30)
SCHEMBL15088794 0.85 CYP19A1 (0.39) CYP19A1DHODHCYP2C9CYP11B1PRKDC
SCHEMBL15088917 0.85 CYP19A1 (0.34) CYP19A1DHODHPIK3CAPRKDC
SCHEMBL15088821 0.84 METAP1 (0.34) PIK3CA
SCHEMBL15088955 0.84 CYP2A6 (0.36) CYP19A1DHODHPRKDCMAPK14MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2013100497-A1 ORGANIC LIGHT-EMITTING COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE USING SAME 주식회사 두산 (KR) 2013-07-04 WO disclosed