SCHEMBL15088903

SCHEMBL15088903

c1ccc(-c2cc(-c3ccccc3)nc(-c3ccc4c(c3)c3cc5c(cc3n4-c3cc(-c4cccnc4)ccn3)N(c3cc(-c4cccnc4)ccn3)c3cccc4cccc-5c34)c2)cc1

nearest known ligand 0.38

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 2/20 0.38
DHODH Q02127 1/20 0.33
PIK3CA P42336 1/20 0.33
PDE6D O43924 1/20 0.32
CYP17A1 P05093 1/20 0.31
CYP11B1 P15538 1/20 0.31
CYP11B2 P19099 1/20 0.31
PRKDC P78527 1/20 0.31
PDE5A O76074 1/20 0.30
PDE4A P27815 1/20 0.30
PDE4B Q07343 1/20 0.30
PDE4C Q08493 1/20 0.30
PDE4D Q08499 1/20 0.30
PDE3B Q13370 1/20 0.30
PDE3A Q14432 1/20 0.30
COMT P21964 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15088815 0.94 PIK3CA (0.36) CYP19A1PIK3CAPDE6DCYP17A1CYP11B1
SCHEMBL15088797 0.92 CYP19A1 (0.40) CYP19A1DHODHPIK3CAPDE6DCYP17A1
SCHEMBL15088917 0.90 CYP19A1 (0.34) CYP19A1DHODHPIK3CAPRKDC
SCHEMBL15088955 0.88 CYP2A6 (0.36) CYP19A1DHODHPDE6DPRKDC
SCHEMBL15089286 0.88 PDE6D (0.40) PIK3CAPDE6DCOMT
SCHEMBL15088787 0.87 CYP11B1 (0.35) CYP19A1PIK3CAPDE6DCYP17A1CYP11B1
SCHEMBL15088795 0.87 PDE6D (0.37) PDE6D
SCHEMBL15088786 0.86 PDE6D (0.38) PDE6D
SCHEMBL15089361 0.86 PDE6D (0.35) PDE6DCOMT
SCHEMBL15089026 0.86 PDE6D (0.35) PDE6DCOMT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2013100497-A1 ORGANIC LIGHT-EMITTING COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE USING SAME 주식회사 두산 (KR) 2013-07-04 WO disclosed