SCHEMBL15089013

SCHEMBL15089013

CC1(C)c2ccccc2-c2cc3c(cc21)N(c1cccc(-c2cccnc2)n1)c1cccc2cccc-3c12

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 1/20 0.36
HSD17B10 Q99714 2/20 0.35
GAA P10253 1/20 0.35
MAPT P10636 1/20 0.35
MAPK1 P28482 1/20 0.35
HTT P42858 1/20 0.35
PDE6D O43924 1/20 0.34
PDK2 Q15119 3/20 0.34
PIM1 P11309 7/20 0.33
MAP3K5 Q99683 1/20 0.33
CASP1 P29466 2/20 0.32
CASP7 P55210 2/20 0.32
GLA P06280 1/20 0.32
HPGD P15428 1/20 0.32
CYP19A1 P11511 1/20 0.32
PIM3 Q86V86 1/20 0.32
PIM2 Q9P1W9 1/20 0.32
TSHR P16473 1/20 0.32
KARS1 Q15046 1/20 0.31
KDM4E B2RXH2 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15089045 0.91 CYP19A1 (0.37) CYP2A6HSD17B10GAAMAPTMAPK1
SCHEMBL15089100 0.88 PDK2 (0.35) CYP2A6HSD17B10GAAMAPTMAPK1
SCHEMBL15089009 0.88 PDE6D (0.35) PDE6D
SCHEMBL15088982 0.87 PDK2 (0.36) CYP2A6HSD17B10GAAMAPTMAPK1
SCHEMBL15089007 0.83 HSD17B10 (0.44) HSD17B10GAAMAPTMAPK1HTT
SCHEMBL15089005 0.81 CNR2 (0.36) GAAMAPTPDE6DPDK2CASP1
SCHEMBL15089004 0.81 KDM4E (0.45) HSD17B10GAAMAPTHTTPDE6D
SCHEMBL15088988 0.81 PDE6D (0.37) GAAPDE6DCASP1CASP7KDM4E
SCHEMBL15088851 0.81 PDE6D (0.37) PDE6D
SCHEMBL15089191 0.80 PDE6D (0.33) PDE6D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2013100497-A1 ORGANIC LIGHT-EMITTING COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE USING SAME 주식회사 두산 (KR) 2013-07-04 WO disclosed