SCHEMBL15089100

SCHEMBL15089100

CC1(C)c2ccccc2-c2cc3c(cc21)N(c1cc(-c2cccnc2)ccn1)c1cccc2cccc-3c12

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDK2 Q15119 3/20 0.35
COMT P21964 1/20 0.34
CYP11B1 P15538 2/20 0.33
CYP17A1 P05093 1/20 0.33
CYP19A1 P11511 1/20 0.33
CYP11B2 P19099 1/20 0.33
BACE1 P56817 2/20 0.32
KCNH2 Q12809 1/20 0.32
CYP2A6 P11509 2/20 0.32
MEN1 O00255 1/20 0.32
PSIP1 O75475 1/20 0.32
AXL P30530 1/20 0.32
MKNK1 Q9BUB5 1/20 0.32
MKNK2 Q9HBH9 1/20 0.32
CDK9 P50750 1/20 0.31
GABRG2 P18507 1/20 0.31
GABRB3 P28472 1/20 0.31
GABRA3 P34903 1/20 0.31
PIK3CA P42336 1/20 0.31
GAA P10253 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15088988 0.92 PDE6D (0.37) COMTGAA
SCHEMBL15089045 0.90 CYP19A1 (0.37) PDK2CYP11B1CYP17A1CYP19A1CYP11B2
SCHEMBL15088982 0.90 PDK2 (0.36) PDK2CYP11B1CYP17A1CYP19A1CYP11B2
SCHEMBL15089013 0.88 CYP2A6 (0.36) PDK2CYP19A1BACE1CYP2A6GAA
SCHEMBL15089007 0.83 HSD17B10 (0.44) CYP11B1CYP11B2GAAMAPTMAPK1
SCHEMBL15089004 0.82 KDM4E (0.45) MEN1GAAMAPTHTTHSD17B10
SCHEMBL15088851 0.80 PDE6D (0.37)
SCHEMBL15089186 0.79 PDE6D (0.36) MEN1GAAMAPT
SCHEMBL15089223 0.78 PDK2 (0.35) PDK2CYP11B1CYP17A1CYP19A1CYP11B2
SCHEMBL15089002 0.77 PDE6D (0.34)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2013100497-A1 ORGANIC LIGHT-EMITTING COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE USING SAME 주식회사 두산 (KR) 2013-07-04 WO disclosed