SCHEMBL15089131

SCHEMBL15089131

Nc1ncc(-c2ccccc2)c2ccccc12

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAP4K4 O95819 3/20 0.47
USP7 Q93009 3/20 0.47
FGFR1 P11362 2/20 0.47
CSF1R P07333 1/20 0.47
PDGFRA P16234 1/20 0.47
LTK P29376 1/20 0.47
KDR P35968 1/20 0.47
MAPK8 P45983 1/20 0.47
CSNK1A1 P48729 1/20 0.47
LIMK1 P53667 1/20 0.47
CDK5 Q00535 1/20 0.47
ACVR1 Q04771 1/20 0.47
TNK2 Q07912 1/20 0.47
AURKB Q96GD4 1/20 0.47
CLK4 Q9HAZ1 1/20 0.47
DYRK1B Q9Y463 1/20 0.47
KDM4E B2RXH2 1/20 0.46
MEN1 O00255 1/20 0.44
NPC1 O15118 1/20 0.44
RAB9A P51151 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28138757 0.83 CYP11B1 (0.53) KDM4EMEN1TDO2ALDH1A1
SCHEMBL12070657 0.81 TOP1 (0.42) MAP4K4USP7FGFR1CSF1RPDGFRA
SCHEMBL10300877 0.76 ADORA2A (0.50) KDM4ENPC1RAB9ALMNAADORA2A
SCHEMBL23579403 0.75 USP7 (0.49) MAP4K4USP7FGFR1KDM4EMEN1
SCHEMBL3243064 0.75 USP7 (0.53) MAP4K4USP7MEN1NPC1RAB9A
SCHEMBL28365426 0.75 BRD4 (0.55) MAP4K4KDRAURKBSMARCA2SMARCA4
SCHEMBL23295110 0.75 KDM4E (0.41) MAP4K4KDM4ENPC1RAB9ALMNA
SCHEMBL22853524 0.75 KDM4E (0.52) KDM4EALDH1A1HSD17B10
SCHEMBL19891116 0.74 MAP4K4 (0.42) MAP4K4USP7
SCHEMBL11978674 0.74 AKT1 (0.44) MEN1NPC1RAB9AKMT2ATDO2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2015125986-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME 주식회사 두산 2015-08-27 WO disclosed
WO-2015093813-A2 ORGANIC COMPOUND, AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME 주식회사 두산 2015-06-25 WO disclosed
WO-2015008940-A1 ORGANIC ELECTROLUMINESCENT DEVICE 주식회사 두산 (KR) 2015-01-22 WO disclosed
WO-2014142488-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT ELEMENT INCLUDING SAME 주식회사 두산 (KR) 2014-09-18 WO disclosed
WO-2014104663-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT ELEMENT COMPRISING SAME 주식회사 두산 (KR) 2014-07-03 WO disclosed
WO-2014104665-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT ELEMENT INCLUDING SAME 주식회사 두산 (KR) 2014-07-03 WO disclosed
WO-2014098455-A1 NOVEL ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT ELEMENT COMPRISING SAME 주식회사 두산 (KR) 2014-06-26 WO disclosed
WO-2014098447-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT ELEMENT COMPRISING SAME 주식회사 두산 (KR) 2014-06-26 WO disclosed
WO-2014092483-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT ELEMENT COMPRISING SAME 주식회사 두산 (KR) 2014-06-19 WO disclosed
WO-2014092481-A1 ORGANIC COMPOUND, AND ORGANIC ELECTROLUMINESCENCE DEVICE COMPRISING SAME 주식회사 두산 (KR) 2014-06-19 WO disclosed
WO-2014081134-A1 NOVEL COMPOUND AND ORGANIC ELECTROLUMINESCENT ELEMENT COMPRISING SAME 주식회사 두산 (KR) 2014-05-30 WO disclosed
WO-2014065498-A1 ORGANIC ELECTROLUMINESCENT DEVICE 주식회사 두산 (KR) 2014-05-01 WO disclosed
WO-2013100497-A1 ORGANIC LIGHT-EMITTING COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE USING SAME 주식회사 두산 (KR) 2013-07-04 WO disclosed