SCHEMBL3243064

SCHEMBL3243064

Nc1ncc(-c2ccccc2)c(N)c1-c1ccccc1

nearest known ligand 0.53

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
USP7 Q93009 9/20 0.53
MEN1 O00255 2/20 0.45
NPC1 O15118 2/20 0.45
RAB9A P51151 2/20 0.45
KMT2A Q03164 2/20 0.45
MAP4K4 O95819 2/20 0.45
TDO2 P48775 2/20 0.41
SMARCA2 P51531 1/20 0.41
SMARCA4 P51532 1/20 0.41
PBRM1 Q86U86 1/20 0.41
LMNA P02545 1/20 0.41
ADORA2A P29274 1/20 0.41
ADORA1 P30542 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23579403 0.84 USP7 (0.49) USP7MEN1NPC1RAB9AKMT2A
SCHEMBL7256621 0.79 HPGDS (0.49) USP7MEN1NPC1RAB9AKMT2A
SCHEMBL3230297 0.78 USP7 (0.49) USP7
SCHEMBL27571466 0.77 USP7 (0.54) USP7MEN1NPC1RAB9AKMT2A
SCHEMBL27573376 0.77 MAP4K4 (0.43) USP7MEN1NPC1RAB9AKMT2A
SCHEMBL15089131 0.75 MAP4K4 (0.47) USP7MEN1NPC1RAB9AKMT2A
SCHEMBL29360194 0.73 GSK3B (0.46) USP7MEN1NPC1RAB9AKMT2A
SCHEMBL4647645 0.73 GSK3B (0.46) USP7MEN1NPC1RAB9AKMT2A
SCHEMBL4905628 0.73 ADORA2A (0.56) MEN1KMT2ALMNAADORA2AADORA1
SCHEMBL29115860 0.72 MAPK1 (0.53) MEN1KMT2ALMNAADORA2AADORA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7745020-B2 Metallic compound and organic electroluminescence device comprising the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2010-06-29 US disclosed
US-20080193795-A1 Metallic Compound and Organic Electroluminescence Device Comprising the Same SAMSUNG ELECTRONICS CO., LTD. (KR) 2008-08-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080193795-A1 Metallic Compound and Organic Electroluminescence Device Comprising the Same PRMT5, CHRM5, PRMT6 USP7 3612/4885MEN1 768/4885NPC1 4385/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.