SCHEMBL15089211

SCHEMBL15089211

c1ccc(-c2ccc(N3c4cc5c(cc4-c4ccc(-c6ccccn6)c6cccc3c46)c3cc(-c4ccccn4)ccc3n5-c3ccc(-c4ccccc4)cc3)cc2)cc1

nearest known ligand 0.33

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
MAPK14 Q16539 1/20 0.33
PIM1 P11309 1/20 0.33
PIM3 Q86V86 1/20 0.33
PDE6D O43924 1/20 0.33
HTR1A P08908 1/20 0.32
HTR7 P34969 1/20 0.32
GRM5 P41594 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15089196 0.96 MAPK14 (0.34) MAPK14PIM1PIM3HTR1AHTR7
SCHEMBL15089219 0.95 MAPK14 (0.36) MAPK14PIM1PIM3HTR1AHTR7
SCHEMBL15089200 0.93 GRM5 (0.36) MAPK14PIM1PIM3HTR1AHTR7
SCHEMBL15089170 0.92 TSHR (0.32) MAPK14PDE6DGRM5
SCHEMBL15089175 0.91 HTR1A (0.34) MAPK14HTR1AHTR7GRM5
SCHEMBL15088894 0.90 GRM5 (0.32) MAPK14GRM5
SCHEMBL15089059 0.90 PDE6D (0.45) MAPK14PIM1PIM3PDE6DHTR1A
SCHEMBL15089239 0.89 PDE6D (0.44) MAPK14PIM1PIM3PDE6DHTR1A
SCHEMBL15089177 0.89 MAPK14 (0.35) MAPK14PIM1PIM3HTR1AHTR7
SCHEMBL15088933 0.88 TSHR (0.31) MAPK14GRM5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2013100497-A1 ORGANIC LIGHT-EMITTING COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE USING SAME 주식회사 두산 (KR) 2013-07-04 WO disclosed