SCHEMBL15089223

SCHEMBL15089223

c1ccc(C2(c3ccccc3)c3ccccc3-c3cc4c(cc32)N(c2ccc(-c3cccnc3)cn2)c2cccc3cccc-4c23)cc1

nearest known ligand 0.35

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
PDK2 Q15119 3/20 0.35
PDE6D O43924 1/20 0.33
CYP2A6 P11509 1/20 0.33
CYP17A1 P05093 1/20 0.33
CYP19A1 P11511 1/20 0.33
CYP11B1 P15538 1/20 0.33
CYP11B2 P19099 1/20 0.33
BACE1 P56817 5/20 0.30
KCNH2 Q12809 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15089229 0.88 CNR2 (0.35) PDK2PDE6DBACE1
SCHEMBL15088982 0.87 PDK2 (0.36) PDK2PDE6DCYP2A6CYP17A1CYP19A1
SCHEMBL15089043 0.84 HTT (0.43) PDE6D
SCHEMBL15089212 0.84 KDM4E (0.43) PDE6D
SCHEMBL15089186 0.82 PDE6D (0.36) PDE6D
SCHEMBL15089076 0.81 PDK2 (0.35) PDK2CYP11B1CYP11B2BACE1KCNH2
SCHEMBL15089180 0.80 PDE6D (0.37) PDE6D
SCHEMBL15089189 0.80 PDE6D (0.51) PDE6D
SCHEMBL15089222 0.80 PDE6D (0.31) PDE6D
SCHEMBL15089213 0.79 KDM4E (0.40) PDE6DCYP19A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2013100497-A1 ORGANIC LIGHT-EMITTING COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE USING SAME 주식회사 두산 (KR) 2013-07-04 WO disclosed