SCHEMBL15089249

SCHEMBL15089249

c1ccc(-n2c3ccc(-c4ccccn4)cc3c3cc4c(cc32)N(c2cccnc2)c2cccc3cccc-4c23)cc1

nearest known ligand 0.38

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
HTT P42858 2/20 0.38
MAPT P10636 2/20 0.38
GAA P10253 1/20 0.38
MAPK1 P28482 1/20 0.38
HSD17B10 Q99714 1/20 0.38
CYP2A6 P11509 1/20 0.34
PDE6D O43924 1/20 0.33
GRM5 P41594 3/20 0.33
DHFR P00374 1/20 0.32
CYP1A2 P05177 2/20 0.32
METAP2 P50579 2/20 0.32
MCL1 Q07820 1/20 0.32
GFER P55789 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32
IRAK4 Q9NWZ3 1/20 0.31
HTR1A P08908 1/20 0.30
HTR7 P34969 1/20 0.30
MAPK14 Q16539 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15089033 0.97 HTT (0.39) HTTMAPTGAAMAPK1HSD17B10
SCHEMBL15089024 0.93 PDE6D (0.39) GAAPDE6DGRM5DHFRIRAK4
SCHEMBL15089254 0.93 GRM5 (0.35) HTTMAPTGAAMAPK1HSD17B10
SCHEMBL15089244 0.91 PDE6D (0.36) MAPTPDE6DGRM5DHFRIRAK4
SCHEMBL15089066 0.90 GRM5 (0.35) HTTMAPTGAAMAPK1HSD17B10
SCHEMBL15089239 0.90 PDE6D (0.44) GAAPDE6DGRM5DHFRIRAK4
SCHEMBL15089154 0.90 HTT (0.41) HTTMAPTGAAMAPK1HSD17B10
SCHEMBL15089079 0.89 PDE6D (0.32) MAPTPDE6DDHFRIRAK4MAPK14
SCHEMBL15089358 0.89 PDE6D (0.39) PDE6DGRM5DHFRHTR1AHTR7
SCHEMBL15089059 0.89 PDE6D (0.45) MAPTGAAHSD17B10PDE6DGRM5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2013100497-A1 ORGANIC LIGHT-EMITTING COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE USING SAME 주식회사 두산 (KR) 2013-07-04 WO disclosed