SCHEMBL15089254

SCHEMBL15089254

c1ccc(-n2c3ccc(-c4ccccn4)cc3c3cc4c(cc32)N(c2cccc(-c3ccc5c(c3)c3ccccc3n5-c3cccnc3)c2)c2cccc3cccc-4c23)cc1

nearest known ligand 0.35

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
GRM5 P41594 3/20 0.35
CYP1A2 P05177 2/20 0.33
METAP2 P50579 2/20 0.33
DHFR P00374 1/20 0.33
GAA P10253 1/20 0.32
MAPT P10636 1/20 0.32
MAPK1 P28482 1/20 0.32
HTT P42858 1/20 0.32
HSD17B10 Q99714 1/20 0.32
CYP2A6 P11509 1/20 0.32
GFER P55789 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32
PDE6D O43924 1/20 0.32
HTR1A P08908 1/20 0.31
HTR7 P34969 1/20 0.31
NPY5R Q15761 1/20 0.31
MDM2 Q00987 1/20 0.30
HRH1 P35367 1/20 0.30
HTR6 P50406 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15089066 0.98 GRM5 (0.35) GRM5CYP1A2METAP2DHFRGAA
SCHEMBL15089360 0.94 PDE6D (0.35) GRM5DHFRPDE6DHTR1AHTR7
SCHEMBL15089032 0.94 PDE6D (0.35) GRM5DHFRPDE6DHTR1AHTR7
SCHEMBL15089142 0.93 MAPT (0.36) CYP1A2METAP2GAAMAPTMAPK1
SCHEMBL15089249 0.93 HTT (0.38) GRM5CYP1A2METAP2DHFRGAA
SCHEMBL15089146 0.93 PDE6D (0.38) CYP1A2METAP2GAAMAPTMAPK1
SCHEMBL15089033 0.92 HTT (0.39) GRM5CYP1A2METAP2DHFRGAA
SCHEMBL15089270 0.91 PDE6D (0.38) CYP1A2METAP2GAAMAPTMAPK1
SCHEMBL15088916 0.91 MAPT (0.37) CYP1A2METAP2GAAMAPTMAPK1
SCHEMBL15089358 0.91 PDE6D (0.39) GRM5DHFRPDE6DHTR1AHTR7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2013100497-A1 ORGANIC LIGHT-EMITTING COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE USING SAME 주식회사 두산 (KR) 2013-07-04 WO disclosed