SCHEMBL15089266

SCHEMBL15089266

c1ccc(-c2ccc3c(c2)c2cc4c(cc2n3-c2nccc(-c3ccccc3)n2)N(c2nccc(-c3ccccc3)n2)c2cccc3cccc-4c23)cc1

nearest known ligand 0.38

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
PDE6D O43924 1/20 0.38
HCRTR1 O43613 5/20 0.32
HCRTR2 O43614 5/20 0.32
PDE10A Q9Y233 1/20 0.32
MAPK8 P45983 2/20 0.31
PIK3CG P48736 2/20 0.31
GSK3B P49841 2/20 0.31
CAMKK2 Q96RR4 2/20 0.31
PLG P00747 1/20 0.30
PLAU P00749 1/20 0.30
DPP4 P27487 1/20 0.30
DKK1 O94907 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15089206 0.94 PDE6D (0.39) PDE6DHCRTR1HCRTR2PDE10AMAPK8
SCHEMBL15089070 0.93 PDE6D (0.33) PDE6DHCRTR1HCRTR2PDE10ADKK1
SCHEMBL15088892 0.92 PDE6D (0.34) PDE6DHCRTR1HCRTR2PDE10ADPP4
SCHEMBL15088833 0.91 PIK3CA (0.33) HCRTR1HCRTR2PDE10AMAPK8PIK3CG
SCHEMBL15089264 0.89 PDE6D (0.41) PDE6DPLGPLAU
SCHEMBL15089295 0.88 PDE6D (0.40) PDE6D
SCHEMBL15089251 0.87 PDE6D (0.34) PDE6D
SCHEMBL15089133 0.86 PDE6D (0.35) PDE6DHCRTR1HCRTR2PDE10ADPP4
SCHEMBL15089262 0.85 PDE6D (0.38) PDE6DPIK3CG
SCHEMBL15089137 0.85 PDE6D (0.42) PDE6D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2013100497-A1 ORGANIC LIGHT-EMITTING COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE USING SAME 주식회사 두산 (KR) 2013-07-04 WO disclosed