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SCHEMBL15089295

SCHEMBL15089295

c1ccc(-c2ccc3c(c2)c2cc4c(cc2n3-c2nc(-c3ccccc3)cc(-c3ccccc3)n2)N(c2nc(-c3ccccc3)cc(-c3ccccc3)n2)c2cccc3cccc-4c23)cc1

nearest known ligand 0.40

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ PDE6D O43924 1/20 0.40
▸ MAPT P10636 2/20 0.31
▸ MAPK1 P28482 1/20 0.31
▸ HTT P42858 1/20 0.31
▸ NPSR1 Q6W5P4 1/20 0.31
▸ L3MBTL1 Q9Y468 1/20 0.31
▸ MEN1 O00255 1/20 0.30
▸ LMNA P02545 1/20 0.30
▸ CYP1A2 P05177 1/20 0.30
▸ CYP2C9 P11712 1/20 0.30
▸ CYP2C19 P33261 1/20 0.30
▸ MAPK10 P53779 1/20 0.30
▸ KMT2A Q03164 1/20 0.30
▸ SMN1; SMN2 Q16637 1/20 0.30
▸ TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15089214 0.94 PDE6D (0.41) PDE6D
SCHEMBL15088951 0.92 PDE6D (0.37) PDE6DMAPTMAPK1NPSR1L3MBTL1
SCHEMBL15089296 0.91 PDE6D (0.41) PDE6D
SCHEMBL15089038 0.90 PDE6D (0.34) PDE6DMAPK1
SCHEMBL15088841 0.90 PDE6D (0.30) PDE6DL3MBTL1
SCHEMBL15089266 0.88 PDE6D (0.38) PDE6D
SCHEMBL15089264 0.86 PDE6D (0.41) PDE6D
SCHEMBL15089117 0.85 PDE6D (0.38) PDE6DMAPTL3MBTL1MEN1LMNA
SCHEMBL15089246 0.85 PDE6D (0.35) PDE6DMAPK1
SCHEMBL15089138 0.84 PDE6D (0.42) PDE6D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2013100497-A1 ORGANIC LIGHT-EMITTING COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE USING SAME 주식회사 두산 (KR) 2013-07-04 — — WO disclosed