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SCHEMBL15089359

SCHEMBL15089359

c1ccc(-n2c3ccc(-c4cccc5ccccc45)cc3c3cc4c(cc32)N(c2ccc(-n3c5ccccc5c5ccccc53)cn2)c2cccc3cccc-4c23)nc1

nearest known ligand 0.35

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ KDM4E B2RXH2 2/20 0.35
▸ ALDH1A1 P00352 1/20 0.35
▸ GAA P10253 1/20 0.35
▸ PDE6D O43924 1/20 0.33
▸ MEN1 O00255 1/20 0.31
▸ LMNA P02545 1/20 0.31
▸ HPGD P15428 1/20 0.31
▸ KMT2A Q03164 1/20 0.31
▸ CASP1 P29466 1/20 0.30
▸ CASP7 P55210 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15089162 0.93 PDE6D (0.39) KDM4EALDH1A1GAAPDE6DMEN1
SCHEMBL15089128 0.93 KDM4E (0.40) KDM4EALDH1A1GAAPDE6DMEN1
SCHEMBL15089052 0.91 NPY5R (0.33) KDM4EALDH1A1GAAPDE6D
SCHEMBL15089253 0.90 KDM4E (0.36) KDM4EALDH1A1GAAPDE6DMEN1
SCHEMBL15089274 0.89 PDE6D (0.40) PDE6D
SCHEMBL15088900 0.89 PDE6D (0.34) KDM4EALDH1A1GAAPDE6D
SCHEMBL15088906 0.86 KDM4E (0.46) KDM4EALDH1A1GAAPDE6DMEN1
SCHEMBL15089135 0.85 KDM4E (0.40) KDM4EALDH1A1GAAPDE6DMEN1
SCHEMBL15089140 0.84 KDM4E (0.36) KDM4EALDH1A1GAAPDE6DMEN1
SCHEMBL15089243 0.84 KDM4E (0.40) KDM4EALDH1A1GAAPDE6DMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2013100497-A1 ORGANIC LIGHT-EMITTING COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE USING SAME 주식회사 두산 (KR) 2013-07-04 — — WO disclosed