SCHEMBL15089140

SCHEMBL15089140

c1ccc(-n2c3ccccc3c3cc4c(cc32)N(c2ccc(-c3cccnc3)cn2)c2cccc3cccc-4c23)nc1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.36
ALDH1A1 P00352 3/20 0.36
GAA P10253 2/20 0.36
VHL P40337 1/20 0.34
HPGD P15428 2/20 0.34
MEN1 O00255 2/20 0.34
KMT2A Q03164 2/20 0.34
LMNA P02545 1/20 0.34
CYP11B1 P15538 2/20 0.33
G6PD P11413 1/20 0.33
MAPK14 Q16539 1/20 0.33
PDE6D O43924 1/20 0.33
CYP2A6 P11509 1/20 0.33
CYP17A1 P05093 2/20 0.32
CYP19A1 P11511 1/20 0.32
CYP11B2 P19099 1/20 0.32
CASP1 P29466 3/20 0.32
CASP7 P55210 2/20 0.32
HSD17B10 Q99714 2/20 0.32
TSHR P16473 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15088899 0.96 CYP11B1 (0.36) KDM4EALDH1A1GAAHPGDCYP11B1
SCHEMBL15089157 0.93 PDE6D (0.36) KDM4EALDH1A1GAAVHLHPGD
SCHEMBL15089240 0.92 MAPT (0.36) KDM4EALDH1A1GAAVHLHPGD
SCHEMBL15089072 0.90 MAPT (0.37) KDM4EALDH1A1GAACYP11B1G6PD
SCHEMBL15089268 0.89 PDE6D (0.36) ALDH1A1LMNACYP11B1G6PDMAPK14
SCHEMBL15089135 0.89 KDM4E (0.40) KDM4EALDH1A1GAAHPGDMEN1
SCHEMBL15088906 0.88 KDM4E (0.46) KDM4EALDH1A1GAAHPGDMEN1
SCHEMBL15088922 0.87 MAPT (0.39) KDM4EALDH1A1GAAHPGDMEN1
SCHEMBL15088787 0.86 CYP11B1 (0.35) KDM4EALDH1A1GAAHPGDMEN1
SCHEMBL15089128 0.86 KDM4E (0.40) KDM4EALDH1A1GAAHPGDMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2013100497-A1 ORGANIC LIGHT-EMITTING COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE USING SAME 주식회사 두산 (KR) 2013-07-04 WO disclosed