Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | TDO2 | P48775 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3435642 | 1.00 | LMNA (0.46) | LMNATP53HTTEPHX1KMT2A | |
| SCHEMBL3435920 | 1.00 | LMNA (0.46) | LMNATP53HTTEPHX1KMT2A | |
| SCHEMBL3435079 | 1.00 | LMNA (0.46) | LMNATP53HTTEPHX1KMT2A | |
| SCHEMBL15078587 | 0.86 | LMNA (0.46) | LMNATP53HTTEPHX1KMT2A | |
| SCHEMBL3435931 | 0.85 | LMNA (0.49) | LMNATP53HTTEPHX1KMT2A | |
| SCHEMBL3434952 | 0.85 | LMNA (0.49) | LMNATP53HTTEPHX1KMT2A | |
| SCHEMBL3435170 | 0.85 | LMNA (0.49) | LMNATP53HTTEPHX1KMT2A | |
| SCHEMBL15078511 | 0.83 | LMNA (0.44) | LMNATP53HTTEPHX1KMT2A | |
| SCHEMBL15078557 | 0.83 | LMNA (0.44) | LMNATP53HTTEPHX1KMT2A | |
| SCHEMBL15078566 | 0.83 | LMNA (0.44) | LMNATP53HTTEPHX1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013100571-A9 | PHENYL CARBAMATE COMPOUNDS FOR USE IN PREVENTING OR TREATING ALS | BIO-PHARM SOLUTIONS CO., LTD. (KR) | 2014-09-18 | — | — | WO | disclosed |
| WO-2013100571-A1 | PHENYL CARBAMATE COMPOUNDS FOR USE IN PREVENTING OR TREATING ALS | BIO-PHARM SOLUTIONS CO., LTD. (KR) | 2013-07-04 | — | — | WO | disclosed |