Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL1509056

N.O=S(=O)(O)CCN1CCOCC1

nearest known ligand 0.96

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.50
MEN1 O00255 1/20 0.50
GLA P06280 1/20 0.47
KDM4E B2RXH2 3/20 0.47
ALDH1A1 P00352 2/20 0.47
SMN1; SMN2 Q16637 2/20 0.42
KEAP1 Q14145 1/20 0.42
HSD17B10 Q99714 2/20 0.41
ALOX15 P16050 1/20 0.39
TSHR P16473 1/20 0.39
PAOX Q6QHF9 1/20 0.39
HPGD P15428 1/20 0.39
DUSP3 P51452 1/20 0.39
USP2 O75604 1/20 0.39
GAA P10253 1/20 0.39
MAPT P10636 1/20 0.39
CA12 O43570 2/20 0.38
CA7 P43166 1/20 0.38
CA14 Q9ULX7 1/20 0.38
CA1 P00915 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18770758 0.98 KMT2A (0.51) KMT2AMEN1GLAKDM4EALDH1A1
SCHEMBL6200 0.98 KMT2A (0.51) KMT2AMEN1GLAKDM4EALDH1A1
SCHEMBL190394 0.96 KMT2A (0.50) KMT2AMEN1GLAKDM4EALDH1A1
SCHEMBL29027430 0.96 KMT2A (0.50) KMT2AMEN1GLAKDM4EALDH1A1
SCHEMBL285411 0.96 KMT2A (0.50) KMT2AMEN1GLAKDM4EALDH1A1
Hydrochloric Acid SCHEMBL5962066 0.96 GLA (0.52) KMT2AMEN1GLAKDM4EALDH1A1
SCHEMBL5492635 0.96 KMT2A (0.50) KMT2AMEN1GLAKDM4EALDH1A1
Water SCHEMBL108075 0.96 KMT2A (0.50) KMT2AMEN1GLAKDM4EALDH1A1
Water SCHEMBL659931 0.96 KMT2A (0.50) KMT2AMEN1GLAKDM4EALDH1A1
Water SCHEMBL1157088 0.96 KMT2A (0.50) KMT2AMEN1GLAKDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023142797-A1 PREPARATION PROCESS FOR SULFONIC ACID-CONTAINING COMPOUND 苏州亚科科技股份有限公司 2023-08-03 WO disclosed
CN-109689730-A Including TROGER alkali and isatin part and there is intrinsic micro porous polymer 陶氏环球技术有限责任公司 2019-04-26 CN disclosed
EP-2293056-A2 A method for analysing a metabolic pathway Target Discovery, Inc. (US) 2011-03-09 EP disclosed
EP-1194768-A4 POLYPEPTIDE FINGERPRINTING METHODS, METABOLIC PROFILING, AND BIOINFORMATICS DATABASE TARGET DISCOVERY INC (US) 2008-03-26 EP disclosed
US-7211376-B2 Polypeptide fingerprinting methods TARGET DISCOVERY, INC. (US) 2007-05-01 US disclosed
US-20050089930-A1 Polypeptide fingerprinting methods TARGET DISCOVERY, INC. (US) 2005-04-28 US disclosed
US-6677114-B1 HIGH RESOLUTION, PRECISION AND SENSITIVITY PROTEOMICS; MULTIDIMENSIONAL CAPILLARY ELECTROPHORESIS, MASS SPECTRO-GRAPHIC FRAGMENTATION AND PROTEIN SEQUENCE TAG IDENTIFICATION TARGET DISCOVERY, INC. 2004-01-13 US disclosed
EP-1194768-A1 POLYPEPTIDE FINGERPRINTING METHODS, METABOLIC PROFILING, AND BIOINFORMATICS DATABASE Target Discovery, Inc. (US) 2002-04-10 EP disclosed
WO-2000063683-A1 POLYPEPTIDE FINGERPRINTING METHODS, METABOLIC PROFILING, AND BIOINFORMATICS DATABASE TARGET DISCOVERY, INC. (US) 2000-10-26 WO disclosed