SCHEMBL190394

SCHEMBL190394

O=S(=O)(O)CCN1CCOCC1.[KH]

nearest known ligand 0.96

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.50
MEN1 O00255 1/20 0.50
GLA P06280 1/20 0.47
KDM4E B2RXH2 3/20 0.47
ALDH1A1 P00352 2/20 0.47
SMN1; SMN2 Q16637 2/20 0.42
KEAP1 Q14145 1/20 0.42
HSD17B10 Q99714 2/20 0.41
ALOX15 P16050 1/20 0.39
TSHR P16473 1/20 0.39
PAOX Q6QHF9 1/20 0.39
HPGD P15428 1/20 0.39
DUSP3 P51452 1/20 0.39
USP2 O75604 1/20 0.39
GAA P10253 1/20 0.39
MAPT P10636 1/20 0.39
CA12 O43570 2/20 0.38
CA7 P43166 1/20 0.38
CA14 Q9ULX7 1/20 0.38
CA1 P00915 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18770758 0.98 KMT2A (0.51) KMT2AMEN1GLAKDM4EALDH1A1
SCHEMBL6200 0.98 KMT2A (0.51) KMT2AMEN1GLAKDM4EALDH1A1
Hydrochloric Acid SCHEMBL5962066 0.96 GLA (0.52) KMT2AMEN1GLAKDM4EALDH1A1
Water SCHEMBL659931 0.96 KMT2A (0.50) KMT2AMEN1GLAKDM4EALDH1A1
Water SCHEMBL1157088 0.96 KMT2A (0.50) KMT2AMEN1GLAKDM4EALDH1A1
SCHEMBL5492635 0.96 KMT2A (0.50) KMT2AMEN1GLAKDM4EALDH1A1
Ammonia Solution, Strong SCHEMBL1509056 0.96 KMT2A (0.50) KMT2AMEN1GLAKDM4EALDH1A1
Water SCHEMBL108075 0.96 KMT2A (0.50) KMT2AMEN1GLAKDM4EALDH1A1
SCHEMBL29027430 0.96 KMT2A (0.50) KMT2AMEN1GLAKDM4EALDH1A1
SCHEMBL285411 0.96 KMT2A (0.50) KMT2AMEN1GLAKDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118139435-A Perovskite solar cell module with buried bottom interface modification and preparation method 中南大学 2024-06-04 CN disclosed
US-20210207153-A1 SYSTEMS AND METHODS FOR EDITING A PLANT GENOME PIONEER HI-BRED INTERNATIONAL, INC. (US) 2021-07-08 US disclosed
WO-2021067415-A1 NDUFS2 SUBUNIT KNOCKOUT HUMAN CELL LINE VIRGINIA TECH INTELLECTUAL PROPERTIES INC. (US) 2021-04-08 WO disclosed
US-9637524-B2 Proteolysis-resistant capsid of chimeric hepatitis E virus as an oral delivery vector THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2017-05-02 US disclosed
EP-2400982-B1 MULTIPLE ANTIGEN DELIVERY SYSTEM USING HEPATITIS E VIRUS-LIKE PARTICLE UNIV CALIFORNIA (US) 2016-05-11 EP disclosed
US-20150118319-A1 PROTEOLYSIS-RESISTANT CAPSID OF CHIMERIC HEPATITIS E VIRUS AS AN ORAL DELIVERY VECTOR UNIV CALIFORNIA (US) 2015-04-30 US disclosed
US-8906863-B2 Proteolysis-resistant capsid of chimeric hepatitis E virus as an oral delivery vector THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2014-12-09 US disclosed
US-8906862-B2 Multiple antigen delivery system using hepatitis E virus-like particle THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2014-12-09 US disclosed
US-20120301494-A1 PROTEOLYSIS-RESISTANT CAPSID OF CHIMERIC HEPATITIS E VIRUS AS AN ORAL DELIVERY VECTOR REGENTS OF THE UNIVERSITY OF CALIFORNIA 2012-11-29 US disclosed
US-20120148517-A1 Hair Relaxing and Straightening Compositions INTERNATIONAL FLORA TECHNOLOGIES, LTD. (US) 2012-06-14 US disclosed
EP-0397753-B1 DETERMINATION OF GENETIC SEX IN RUMINANTS USING Y-CHROMOSOME-SPECIFIC POLYNUCLEOTIDES ADVANCED RIVERINA HOLDINGS (AU) 1996-06-12 EP disclosed
EP-0618980-A1 COLORIMETRIC DETERMINATION OF PEROXIDASE AND PEROXIDE ABBOTT LABORATORIES (US) 1994-10-12 EP disclosed
WO-1993012253-A1 COLORIMETRIC DETERMINATION OF PEROXIDASE AND PEROXIDE ABBOTT LABORATORIES (US) 1993-06-24 WO disclosed
EP-0276287-B1 SEX DETERMINATION IN RUMINANTS USING Y-CHROMOSOME SPECIFIC POLYNUCLEOTIDES THE AUSTRALIAN NATIONAL UNIVERSITY (AU) 1993-04-07 EP disclosed
EP-0397753-A4 DETERMINATION OF GENETIC SEX IN RUMINANTS USING Y-CHROMOSOME-SPECIFIC POLYNUCLEOTIDES 1991-06-19 EP disclosed
EP-0397753-A1 DETERMINATION OF GENETIC SEX IN RUMINANTS USING Y-CHROMOSOME-SPECIFIC POLYNUCLEOTIDES. ADVANCED RIVERINA HOLDINGS (AU) 1990-11-22 EP disclosed
EP-0276287-A4 SEX DETERMINATION IN RUMINANTS USING Y-CHROMOSOME SPECIFIC POLYNUCLEOTIDES. UNIV AUSTRALIAN (AU) 1989-09-19 EP disclosed
WO-1989007154-A1 DETERMINATION OF GENETIC SEX IN RUMINANTS USING Y-CHROMOSOME-SPECIFIC POLYNUCLEOTIDES ADVANCED RIVERINA HOLDINGS LIMITED (AU) 1989-08-10 WO disclosed
EP-0276287-A1 SEX DETERMINATION IN RUMINANTS USING Y-CHROMOSOME SPECIFIC POLYNUCLEOTIDES. UNIV AUSTRALIAN (AU) 1988-08-03 EP disclosed
WO-1988001300-A1 SEX DETERMINATION IN RUMINANTS USING Y-CHROMOSOME SPECIFIC POLYNUCLEOTIDES THE AUSTRALIAN NATIONAL UNIVERSITY (AU) 1988-02-25 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120148517-A1 Hair Relaxing and Straightening Compositions PDE6G, SHH, DNMT3L KMT2A 268/4885MEN1 863/4885GLA 1584/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.