SCHEMBL15093053

SCHEMBL15093053

N[Si](N)(N)c1c(F)c(F)c(C(F)(F)F)c(F)c1F

nearest known ligand 0.35

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15092855 0.76
SCHEMBL312355 0.76 SMN1; SMN2 (0.42) TSHRSMN1; SMN2
SCHEMBL1639619 0.75 SMN1; SMN2 (0.35) TSHRSMN1; SMN2
SCHEMBL18234132 0.74 SMN1; SMN2 (0.32) TSHRSMN1; SMN2
SCHEMBL13231916 0.74 TSHR (0.32) TSHRSMN1; SMN2
SCHEMBL13231884 0.74 TSHR (0.32) TSHRSMN1; SMN2
Perfluorotoluene SCHEMBL308464 0.73 SMN1; SMN2 (0.41) TSHRSMN1; SMN2
SCHEMBL24227301 0.72 SMN1; SMN2 (0.34) TSHRSMN1; SMN2
SCHEMBL7868555 0.72 SMN1; SMN2 (0.34) TSHRSMN1; SMN2
SCHEMBL24227302 0.70 TSHR (0.33) TSHRSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150141571-A1 WATER-REPELLENT AND OIL-REPELLENT COATING, AND FORMATION METHOD THEREOF TOYOTA JIDOSHA KABUSHIKI KAISHA (JP) 2015-05-21 US claimed
US-20150141571-A1 WATER-REPELLENT AND OIL-REPELLENT COATING, AND FORMATION METHOD THEREOF TOYOTA JIDOSHA KABUSHIKI KAISHA (JP) 2015-05-21 US disclosed
US-20130178580-A1 WATER-REPELLENT AND OIL-REPELLENT COATING, AND FORMATION METHOD THEREOF TOYOTA JIDOSHA KABUSHIKI KAISHA (JP) 2013-07-11 US disclosed