Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.66 |
| ▸ | HSD17B10 | Q99714 | 9/20 | 0.66 |
| ▸ | TSHR | P16473 | 6/20 | 0.60 |
| ▸ | RAB9A | P51151 | 3/20 | 0.58 |
| ▸ | HPGD | P15428 | 3/20 | 0.58 |
| ▸ | NPC1 | O15118 | 3/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.58 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.58 |
| ▸ | GLA | P06280 | 2/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.57 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | RELA | Q04206 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14030807 | 0.91 | ALDH1A1 (0.60) | ALDH1A1HSD17B10TSHRRAB9AHPGD | |
| SCHEMBL14029372 | 0.91 | ALDH1A1 (0.60) | ALDH1A1HSD17B10TSHRRAB9AHPGD | |
| SCHEMBL14029379 | 0.91 | ALDH1A1 (0.60) | ALDH1A1HSD17B10TSHRRAB9AHPGD | |
| SCHEMBL11778352 | 0.91 | ALDH1A1 (0.70) | ALDH1A1HSD17B10TSHRRAB9AHPGD | |
| SCHEMBL14181299 | 0.91 | ALDH1A1 (0.64) | ALDH1A1HSD17B10TSHRRAB9AHPGD | |
| SCHEMBL10389101 | 0.86 | ALDH1A1 (0.67) | ALDH1A1HSD17B10TSHRRAB9AHPGD | |
| SCHEMBL3197843 | 0.82 | ALDH1A1 (0.72) | ALDH1A1HSD17B10TSHRRAB9AHPGD | |
| SCHEMBL30094641 | 0.82 | ALDH1A1 (0.72) | ALDH1A1HSD17B10TSHRRAB9AHPGD | |
| SCHEMBL1805376 | 0.82 | ALDH1A1 (0.80) | ALDH1A1HSD17B10TSHRRAB9AHPGD | |
| SCHEMBL23484459 | 0.79 | TDP1 (0.65) | ALDH1A1HSD17B10TSHRRAB9AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2289962-A2 | Polyurea compositions and compounds for the preparation thereof | Sawyer, Kenneth I. (US) | 2011-03-02 | — | — | EP | claimed |
| US-20080194859-A1 | Polyurea Compositions and Compounds for the Preparation Thereof | Sawyer, Kenneth I. (US) | 2008-08-14 | — | — | US | claimed |
| EP-1751206-A2 | POLYUREA COMPOSITIONS AND COMPOUNDS FOR THE PREPARATION THEREOF | Sawyer, Kenneth I. (US) | 2007-02-14 | — | — | EP | claimed |
| WO-2005113487-A2 | POLYUREA COMPOSITIONS AND COMPOUNDS FOR THE PREPARATION THEREOF | SAWYER KENNETH I (US) | 2005-12-01 | — | — | WO | claimed |
| EP-2289962-A2 | Polyurea compositions and compounds for the preparation thereof | Sawyer, Kenneth I. (US) | 2011-03-02 | — | — | EP | disclosed |
| US-20080264297-A1 | Concentrated Dye Solution | ARCHROMA IP GMBH (CH) | 2008-10-30 | — | — | US | disclosed |
| US-20080264297-A1 | Concentrated Dye Solution | ARCHROMA IP GMBH (CH) | 2008-10-30 | — | — | US | disclosed |
| US-20080194859-A1 | Polyurea Compositions and Compounds for the Preparation Thereof | Sawyer, Kenneth I. (US) | 2008-08-14 | — | — | US | disclosed |
| US-20080194859-A1 | Polyurea Compositions and Compounds for the Preparation Thereof | Sawyer, Kenneth I. (US) | 2008-08-14 | — | — | US | disclosed |
| US-20080194859-A1 | Polyurea Compositions and Compounds for the Preparation Thereof | Sawyer, Kenneth I. (US) | 2008-08-14 | — | — | US | disclosed |
| US-7371831-B2 | Polyazo, disazo, trisazo, triazine, hair and cationic dyes | CLARIANT FINANCE (BVI) LIMITED (VG) | 2008-05-13 | — | — | US | disclosed |
| US-7371831-B2 | Polyazo, disazo, trisazo, triazine, hair and cationic dyes | CLARIANT FINANCE (BVI) LIMITED (VG) | 2008-05-13 | — | — | US | disclosed |
| US-20070251030-A1 | Concentrated Dye Solution | CLARIANT FINANCE (BVI) LIMITED (VG) | 2007-11-01 | — | — | US | disclosed |
| US-20070251030-A1 | Concentrated Dye Solution | CLARIANT FINANCE (BVI) LIMITED (VG) | 2007-11-01 | — | — | US | disclosed |
| EP-1751206-A2 | POLYUREA COMPOSITIONS AND COMPOUNDS FOR THE PREPARATION THEREOF | Sawyer, Kenneth I. (US) | 2007-02-14 | — | — | EP | disclosed |
| WO-2005113487-A2 | POLYUREA COMPOSITIONS AND COMPOUNDS FOR THE PREPARATION THEREOF | SAWYER KENNETH I (US) | 2005-12-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080194859-A1 | Polyurea Compositions and Compounds for the Preparation Thereof | PUF60, PCNA, PARG | ALDH1A1 2747/4885HSD17B10 4631/4885TSHR 4474/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.