⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL351538 | 0.85 | ADRA2A (0.34) | — | |
| SCHEMBL353044 | 0.80 | ADRA2A (0.32) | — | |
| SCHEMBL7624696 | 0.80 | — | — | |
| SCHEMBL351887 | 0.80 | ADRA2A (0.32) | — | |
| SCHEMBL10410293 | 0.78 | ADRA2A (0.32) | — | |
| SCHEMBL9003861 | 0.78 | ADRA2A (0.32) | — | |
| SCHEMBL381129 | 0.78 | ADRA2A (0.32) | — | |
| SCHEMBL9219543 | 0.78 | ADRA2A (0.31) | — | |
| SCHEMBL471908 | 0.78 | ADRA2A (0.32) | — | |
| SCHEMBL27966021 | 0.78 | ADRA2A (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109563045-B | Pd (II) -catalysed enantioselective beta-methylene C (sp) 3 ) -H bond activation | 斯克里普斯研究学院 | 2022-08-23 | — | — | CN | disclosed |
| CN-109563045-A | Pd (II) -catalyzed enantioselectivity β -methylene C (sp)3) -H bond activation | 斯克里普斯研究学院 | 2019-04-02 | — | — | CN | disclosed |
| CN-108728205-A | A kind of volatile rust preventive oil | 南京科润工业介质股份有限公司 | 2018-11-02 | — | — | CN | disclosed |
| US-9868822-B2 | Cross-linked polymers and medical products derived from nucleophilically activated polyoxazoline | GATT TECHNOLOGIES B.V. (NL) | 2018-01-16 | — | — | US | disclosed |
| CN-104024306-B | The conjugate and its medical application of polyoxazoline polymer and preparation method thereof, these polymer | 根特大学 | 2017-06-13 | — | — | CN | disclosed |
| US-20160319075-A1 | CROSS-LINKED POLYMERS AND MEDICAL PRODUCTS DERIVED FROM NUCLEOPHILICALLY ACTIVATED POLYOXAZOLINE | BENDER ANALYTICAL HOLDING B.V. (NL) | 2016-11-03 | — | — | US | disclosed |
| CN-104271638-B | Come from cross-linked polymer and the medical products of nucleophilic reactivity polyoxazoline | 本德尔分析控股公司 | 2016-11-02 | — | — | CN | disclosed |
| US-9416228-B2 | Cross-linked polymers and medical products derived from nucleophilically activated polyoxazoline | BENDER ANALYTICAL HOLDING B.V. (NL) | 2016-08-16 | — | — | US | disclosed |
| EP-2825582-B1 | CROSS-LINKED POLYMERS AND MEDICAL PRODUCTS DERIVED FROM NUCLEOPHILICALLY ACTIVATED POLYOXAZOLINE | BENDER ANALYTICAL HOLDING BV (NL) | 2016-01-13 | — | — | EP | disclosed |
| US-9180202-B2 | Polyoxazoline polymers and methods for their preparation, conjugates of these polymers and medical uses thereof | UNIVERSITEIT GENT (BE) | 2015-11-10 | — | — | US | disclosed |
| US-20150045507-A1 | CROSS-LINKED POLYMERS AND MEDICAL PRODUCTS DERIVED FROM NUCLEOPHILICALLY ACTIVATED POLYOXAZOLINE | BENDER ANALYTICAL HOLDING B.V. (NL) | 2015-02-12 | — | — | US | disclosed |
| US-20150025196-A1 | POLYOXAZOLINE POLYMERS AND METHODS FOR THEIR PREPARATION, CONJUGATES OF THESE POLYMERS AND MEDICAL USES THEREOF | UNIVERSITEIT GENT (BE) | 2015-01-22 | — | — | US | disclosed |
| EP-2825582-A1 | CROSS-LINKED POLYMERS AND MEDICAL PRODUCTS DERIVED FROM NUCLEOPHILICALLY ACTIVATED POLYOXAZOLINE | Bender Analytical Holding B.V. (NL) | 2015-01-21 | — | — | EP | disclosed |
| CN-104271638-A | Cross-linked polymers and medical products derived from nucleophilically activated polyoxazoline | BENDER ANALYTICAL HOLDING BV | 2015-01-07 | — | — | CN | disclosed |
| EP-2800773-A1 | POLYOXAZOLINE POLYMERS AND METHODS FOR THEIR PREPARATION, CONJUGATES OF THESE POLYMERS AND MEDICAL USES THEREOF | Universiteit Gent (BE) | 2014-11-12 | — | — | EP | disclosed |
| CN-104024306-A | POLYOXAZOLINE POLYMERS AND METHODS FOR THEIR PREPARATION, CONJUGATES OF THESE POLYMERS AND MEDICAL USES THEREOF | UNIV GENT | 2014-09-03 | — | — | CN | disclosed |
| WO-2013137736-A1 | CROSS-LINKED POLYMERS AND MEDICAL PRODUCTS DERIVED FROM NUCLEOPHILICALLY ACTIVATED POLYOXAZOLINE | BENDER ANALYTICAL HOLDING B.V. (NL) | 2013-09-19 | — | — | WO | disclosed |
| WO-2013103297-A1 | POLYOXAZOLINE POLYMERS AND METHODS FOR THEIR PREPARATION, CONJUGATES OF THESE POLYMERS AND MEDICAL USES THEREOF | UNIVERSITEIT GENT (BE) | 2013-07-11 | — | — | WO | disclosed |