⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9616743 | 0.97 | POLB (0.43) | — | |
| Hydrochloric Acid SCHEMBL10556422 | 0.97 | POLB (0.43) | — | |
| Alcohol SCHEMBL27736402 | 0.90 | NPSR1 (0.40) | — | |
| SCHEMBL10860376 | 0.83 | ADRB2 (0.50) | — | |
| Hydrochloric Acid SCHEMBL11388590 | 0.81 | ADRB2 (0.48) | — | |
| SCHEMBL11814771 | 0.80 | ADRB2 (0.46) | — | |
| SCHEMBL11806515 | 0.76 | ADRB2 (0.55) | — | |
| SCHEMBL135077 | 0.75 | MEN1 (0.61) | — | |
| SCHEMBL20245672 | 0.74 | — | — | |
| SCHEMBL1408760 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2029580-B1 | NOVEL INDOL-PYRROL DERIVATIVES FOR THE TREATMENT OF PROLIFERATIVE AND INFLAMMATORY DISEASES | SCHEBO BIOTECH AG (DE) | 2010-06-16 | — | — | EP | claimed |
| EP-2029580-A1 | NOVEL INDOL-PYRROL DERIVATIVES FOR THE TREATMENT OF PROLIFERATIVE AND INFLAMMATORY DISEASES | ScheBo Biotech AG (DE) | 2009-03-04 | — | — | EP | claimed |
| WO-2007134578-A1 | NOVEL INDOL-PYRROL DERIVATIVES FOR THE TREATMENT OF PROLIFERATIVE AND INFLAMMATORY DISEASES | SCHEBO BIOTECH AG (DE) | 2007-11-29 | — | — | WO | claimed |
| US-11827616-B2 | Heterocyclic compounds as pesticides | DISCOVERY PURCHASER CORPORATION (US) | 2023-11-28 | — | — | US | disclosed |
| US-20230203018-A1 | COVALENT INHIBITORS OF KRAS | ARAXES PHARMA LLC (US) | 2023-06-29 | — | — | US | disclosed |
| US-20200062729-A1 | NOVEL HETEROCYCLIC COMPOUNDS AS PESTICIDES | DISCOVERY PURCHASER CORPORATION | 2020-02-27 | — | — | US | disclosed |
| US-10138207-B2 | Benzomorphan analogs and the use thereof | PURDUE PHARMA, L.P. (US) | 2018-11-27 | — | — | US | disclosed |
| US-20140329858-A1 | Cyclic Urea Derivatives As Androgen Receptor Antagonists | NOVARTIS AG (CH) | 2014-11-06 | — | — | US | disclosed |
| US-20140274903-A1 | USE OF GALACTOSE OXIDASE FOR SELECTIVE CHEMICAL CONJUGATION OF PROTRACTOR MOLECULES TO PROTEINS OF THERAPEUTIC INTEREST | NOVO NORDISK HEALTHCARE AG (CH) | 2014-09-18 | — | — | US | disclosed |
| US-20140274903-A1 | USE OF GALACTOSE OXIDASE FOR SELECTIVE CHEMICAL CONJUGATION OF PROTRACTOR MOLECULES TO PROTEINS OF THERAPEUTIC INTEREST | NOVO NORDISK HEALTHCARE AG (CH) | 2014-09-18 | — | — | US | disclosed |
| US-20140274903-A1 | USE OF GALACTOSE OXIDASE FOR SELECTIVE CHEMICAL CONJUGATION OF PROTRACTOR MOLECULES TO PROTEINS OF THERAPEUTIC INTEREST | NOVO NORDISK HEALTHCARE AG (CH) | 2014-09-18 | — | — | US | disclosed |
| EP-0268245-A2 | Process for the preparation of eburnamenine oxime derivatives | SANWA KAGAKU KENKYUSHO CO., LTD. (JP) | 1988-05-25 | — | — | EP | disclosed |
| EP-0236151-A1 | Symmetrically O-disubstituted oximes of benzocondensed beta-diketocycloalkenes, processes for their preparation and their use as medicaments | PANMEDICA S.A. (FR) | 1987-09-09 | — | — | EP | disclosed |
| US-4593027-A | 3-aryl-7-chloro-3,4-dihydroacridine-1,9(2H,10H)-dione 1-oximes and 1-hydrazone derivatives, their salts, a process for their preparation, agents containing them and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1986-06-03 | — | — | US | disclosed |
| EP-0082058-B1 | ETHERS OF OXIMES OF 1-PYRIDYL-3-PENTANONE, PROCESS FOR THEIR PREPARATION AND THEIR USE AS A DRUG | UNIVABLOT (FR) | 1985-08-07 | — | — | EP | disclosed |
| EP-0082058-A1 | Ethers of oximes of 1-pyridyl-3-pentanone, process for their preparation and their use as a drug | UNIVABLOT (FR) | 1983-06-22 | — | — | EP | disclosed |
| US-4234572-A | AMINOGLYCOSIDE ANTIBIOTICS | BAYER AKTIENGESELLSCHAFT (DE) | 1980-11-18 | — | — | US | disclosed |
| US-4179516-A | Ethers of 3,4-dihydro-1-benzoxepin-5-one oxime to treat intestinal disorders | ALBERT ROLLAND, S.A. (FR) | 1979-12-18 | — | — | US | disclosed |
| EP-0002450-A1 | 1-N-substituted-4,6-di-O-(aminoglycosyl)-1,3-diamino-cyclitol derivatives, process for preparing them and medicaments containing them | BAYER AG (DE) | 1979-06-27 | — | — | EP | disclosed |
| US-4029808-A | Thienyl phenyl O-(aminoalkyl)-ketone oxime and furyl phenyl O-(aminoalkyl)-ketone oxime coronary vasodilators | C.E.R.P.H.A. A FRENCH SOCIETY ORGANISED UNDER THE LAWS OF FRANCE (FR) | 1977-06-14 | — | — | US | disclosed |