Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 10/20 | 0.62 |
| ▸ | CHRM1 | P11229 | 10/20 | 0.62 |
| ▸ | CHRM3 | P20309 | 9/20 | 0.62 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.62 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Penthienate SCHEMBL31393386 | 0.85 | CHRM1 (0.68) | CHRM2CHRM1CHRM3CHRM4SLC6A3 | |
| Penthienate SCHEMBL250881 | 0.84 | CHRM1 (0.67) | CHRM2CHRM1CHRM3CHRM4SLC6A3 | |
| Penthienate SCHEMBL28086303 | 0.81 | CHRM1 (0.62) | CHRM2CHRM1CHRM3CHRM4SLC6A3 | |
| SCHEMBL9878642 | 0.80 | CHRM2 (0.63) | CHRM2CHRM1CHRM3CHRM4SLC6A3 | |
| SCHEMBL2795158 | 0.79 | CHRM2 (0.73) | CHRM2CHRM1CHRM3CHRM4SLC6A3 | |
| SCHEMBL1234853 | 0.77 | CHRM3 (0.63) | CHRM2CHRM1CHRM3CHRM4ALDH1A1 | |
| SCHEMBL7274074 | 0.76 | CHRM3 (0.54) | CHRM2CHRM1CHRM3CHRM4ALDH1A1 | |
| SCHEMBL1235445 | 0.76 | CHRM3 (0.65) | CHRM2CHRM1CHRM3CHRM4LMNA | |
| SCHEMBL7278370 | 0.75 | CHRM3 (0.56) | CHRM2CHRM1CHRM3CHRM4SLC6A3 | |
| SCHEMBL7277593 | 0.75 | CHRM2 (0.53) | CHRM2CHRM1CHRM3CHRM4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8481518-B2 | Quaternary antimuscarinic compounds for the treatment of bladder diseases | UNIVERSITY OF ROCHESTER (US) | 2013-07-09 | — | — | US | disclosed |