Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 11/20 | 0.62 |
| ▸ | CHRM2 | P08172 | 10/20 | 0.62 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.62 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.62 |
| ▸ | CHRM3 | P20309 | 10/20 | 0.62 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | SCN1A | P35498 | 2/20 | 0.42 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.42 |
| ▸ | SCN3A | Q9NY46 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Penthienate SCHEMBL31393386 | 0.95 | CHRM1 (0.68) | CHRM1CHRM2SLC6A3KCNH2CHRM3 | |
| Penthienate SCHEMBL250881 | 0.94 | CHRM1 (0.67) | CHRM1CHRM2SLC6A3KCNH2CHRM3 | |
| SCHEMBL15095409 | 0.81 | CHRM2 (0.62) | CHRM1CHRM2SLC6A3KCNH2CHRM3 | |
| SCHEMBL2795158 | 0.79 | CHRM2 (0.73) | CHRM1CHRM2SLC6A3KCNH2CHRM3 | |
| Oxyphenonium SCHEMBL250615 | 0.77 | CHRM2 (1.00) | CHRM1CHRM2SLC6A3KCNH2CHRM3 | |
| Oxyphenonium SCHEMBL250614 | 0.77 | CHRM2 (1.00) | CHRM1CHRM2SLC6A3KCNH2CHRM3 | |
| Oxyphenonium SCHEMBL2030870 | 0.76 | CHRM2 (0.98) | CHRM1CHRM2SLC6A3KCNH2CHRM3 | |
| Oxyphenonium SCHEMBL248890 | 0.76 | CHRM2 (0.98) | CHRM1CHRM2SLC6A3KCNH2CHRM3 | |
| Penthienate SCHEMBL5886141 | 0.76 | CHRM1 (0.49) | CHRM1CHRM2SLC6A3KCNH2CHRM3 | |
| SCHEMBL1234853 | 0.74 | CHRM3 (0.63) | CHRM1CHRM2CHRM3CHRM4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103492389-B | Pyrazolo [4,3-d] pyrimidine as inhibitors of kinases | 原真股份有限公司 | 2016-09-14 | — | — | CN | disclosed |