Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 6/20 | 0.56 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.56 |
| ▸ | PABPC1 | P11940 | 2/20 | 0.56 |
| ▸ | CHRM5 | P08912 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.56 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | BLM | P54132 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14652328 | 0.86 | CHRM2 (0.77) | CHRM2CHRM1PABPC1CHRM5MEN1 | |
| SCHEMBL14507225 | 0.76 | CHRM2 (0.80) | CHRM2CHRM1PABPC1CHRM5MEN1 | |
| SCHEMBL4297790 | 0.73 | CYP19A1 (0.70) | CHRM2CHRM1PABPC1CHRM5MEN1 | |
| SCHEMBL16517900 | 0.73 | CYP19A1 (0.70) | CHRM2CHRM1PABPC1CHRM5MEN1 | |
| SCHEMBL23494999 | 0.73 | CYP2D6 (0.76) | CHRM2CHRM1CHRM5MEN1KMT2A | |
| SCHEMBL22394824 | 0.73 | CYP2D6 (0.76) | CHRM2CHRM1CHRM5MEN1KMT2A | |
| SCHEMBL22394825 | 0.73 | CYP2D6 (0.76) | CHRM2CHRM1CHRM5MEN1KMT2A | |
| SCHEMBL22394823 | 0.73 | CYP2D6 (0.76) | CHRM2CHRM1CHRM5MEN1KMT2A | |
| SCHEMBL19136281 | 0.73 | CYP2D6 (0.76) | CHRM2CHRM1CHRM5MEN1KMT2A | |
| SCHEMBL23494998 | 0.73 | CYP2D6 (0.76) | CHRM2CHRM1CHRM5MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8481518-B2 | Quaternary antimuscarinic compounds for the treatment of bladder diseases | UNIVERSITY OF ROCHESTER (US) | 2013-07-09 | — | — | US | disclosed |