Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.61 |
| ▸ | RAB9A | P51151 | 4/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | ELANE | P08246 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | ESR1 | P03372 | 1/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1507827 | 0.95 | ELANE (0.59) | MAPTTDP1L3MBTL1RAB9ANPSR1 | |
| SCHEMBL10057842 | 0.89 | ESR1 (0.65) | MAPTTDP1L3MBTL1RAB9ANPSR1 | |
| SCHEMBL12433918 | 0.89 | ELANE (0.53) | MAPTTDP1L3MBTL1NPSR1MEN1 | |
| SCHEMBL13242039 | 0.89 | LMNA (0.65) | MAPTTDP1L3MBTL1RAB9ANPSR1 | |
| SCHEMBL1507621 | 0.88 | LMNA (0.59) | MAPTTDP1L3MBTL1RAB9AMEN1 | |
| SCHEMBL337701 | 0.88 | MAPT (0.59) | MAPTTDP1L3MBTL1RAB9ANPSR1 | |
| SCHEMBL19431688 | 0.87 | ELANE (0.51) | MAPTTDP1L3MBTL1RAB9ANPSR1 | |
| SCHEMBL27905707 | 0.86 | ELANE (0.61) | MAPTTDP1L3MBTL1RAB9ANPSR1 | |
| Ammonia Solution, Strong SCHEMBL22832179 | 0.86 | MAPT (0.58) | MAPTTDP1L3MBTL1RAB9ANPSR1 | |
| SCHEMBL14039418 | 0.84 | ELANE (0.59) | MAPTTDP1L3MBTL1RAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8481238-B2 | Electrophotographic photoreceptors, electrophotographic photoreceptor cartridge, and image-forming apparatus | MITSUBISHI CHEMICAL CORPORATION (JP) | 2013-07-09 | — | — | US | disclosed |